Nebenwirkungen · Zaltrap
ZALTRAP 25 mg/ml concentrate for solution for infusion · Abschnitt 4.8 · PDF-Seite 14
HOS-215788 · Präparat HOS-155534
Diarrhoea and dehydration In the pivotal study of MCRC patients, diarrhoea (all grades) has been observed in 69.2 % of patients treated with ZALTRAP/FOLFIRI and 56.5 % of patients treated with placebo/FOLFIRI. Dehydration (all grades) has been observed in 9.0 % of patients treated with ZALTRAP/FOLFIRI and 3.0 % of patients treated with placebo/FOLFIRI. Grade 3-4 diarrhoea was reported in 19.3 % of patients treated with the ZALTRAP/FOLFIRI regimen compared to 7.8 % of patients treated with the placebo/FOLFIRI regimen. Grade 3-4 dehydration was reported in 4.3 % of patients treated with the ZALTRAP/FOLFIRI regimen compared to 1.3 % of patients treated with the placebo/FOLFIRI regimen (see section 4.4).
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Version 2024-08-29T14:23:00Z · SHA-256 5b4c1b4848635140cdb6155c414b72c6acf77bc314124cac5763c972a8858b1a · Passage c9f7e19535994d7a7806b0a31366c275490b8c86f88855b9c72b5245c6ef1996 · Zeichen 17208–17917 im Abschnitt