Wechselwirkungen · Lumeblue (previously Methylthioninium chloride Cosmo)
Lumeblue 25 mg prolonged-release tablets · Abschnitt 4.5 · PDF-Seite 4–5
HOS-220131 · Präparat HOS-216547
4 This medicinal product may be coadministered with anaesthetics / analgesics and/or sedative / anxiolytic medicinal products, often used during colonoscopy which are cleared through hepatic CYPs reactions such as: midazolam, propofol, diazepam, diphenhydramine, promethazine, meperidine, and fentanyl. The clinical consequences of changes in plasma concentrations of co-administered medicinal products which are substrates of these metabolic enzymes and transporters are not known but cannot be excluded.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): propofol (HOS-109374) diazepam (HOS-085904) promethazine (HOS-144413) meperidine (HOS-114839) fentanyl (HOS-086196) diphenhydramine (HOS-084528) midazolam (HOS-086167)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-06-17T16:40:00Z · SHA-256 621188d5f64a4490fe97b9da8aa94ea37b740fe8ff7b61603be8af2b1f01a404 · Passage cb58ca39a475de047b2abd91a0640c6cf62fd8446d293e042ac393662bd479c4 · Zeichen 1872–2378 im Abschnitt