Wechselwirkungen · Accofil
Accofil 70 MU/0.73 ml solution for injection/infusion in pre-filled syringe · Abschnitt 4.5 · PDF-Seite 67
HOS-222017 · Präparat HOS-216908
The safety and efficacy of filgrastim given on the same day as myelosuppressive cytotoxic chemotherapy have not been definitively established. In view of the sensitivity of rapidly dividing myeloid cells to myelosuppressive cytotoxic chemotherapy, the use of filgrastim is not recommended in the period from 24 hours before to 24 hours after chemotherapy. Preliminary evidence from a small number of patients treated concomitantly with filgrastim and 5-Fluorouracil indicates that the severity of neutropenia may be exacerbated.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): fluorouracil (HOS-086023)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-11-25T15:11:00Z · SHA-256 c3518f7b95bc3dd24963f91afa5cd0272badfcd4a5f8943510b2f417086a82ed · Passage c13fe508b31bbca4cf35f6c24c3fca5a1f3d22b23242fa90a50bc8f363292b5d · Zeichen 0–528 im Abschnitt