Wechselwirkungen · Pemetrexed Pfizer (previously Pemetrexed Hospira)
Pemetrexed Pfizer 100 mg powder for concentrate for solution for infusion Pemetrexed Pfizer 500 mg powder for concentrate for solution for infusion Pemetrexed Pfizer 1,000 mg powder for concentrate for solution for infusion · Abschnitt 4.5 · PDF-Seite 7
HOS-222236 · Präparat HOS-216974
In the absence of data regarding potential interaction with NSAIDs having longer half-lives such as piroxicam or rofecoxib, the concomitant administration with pemetrexed in patients with mild to moderate renal insufficiency should be interrupted for at least 5 days prior to, on the day of, and at least 2 days following pemetrexed administration (see section 4.4). If concomitant administration of NSAIDs is necessary, patients should be monitored closely for toxicity, especially myelosuppression and gastrointestinal toxicity.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): piroxicam (HOS-110101) rofecoxib (HOS-113241)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2026-01-15T12:00:00Z · SHA-256 1e21d1636b4dab0f95d85442ea7bbdc41322d5a1c88cc6e49dc7195b37822944 · Passage 1ae49fcc20f8a204e2a36b860e0a4f750dde041241287b576c3d415b4ef58fd1 · Zeichen 1578–2108 im Abschnitt