Wirkstoffe & Arzneimittelsicherheit

Nebenwirkungen · Amgevita

AMGEVITA 20 mg solution for injection in pre-filled syringe AMGEVITA 40 mg solution for injection in pre-filled syringe AMGEVITA 80 mg solution for injection in pre-filled syringe AMGEVITA 40 mg solution for injection in pre-filled pen AMGEVITA 80 mg solution for injection in pre-filled pen · Abschnitt 4.8 · PDF-Seite 76

HOS-224965 · Präparat HOS-217372

In controlled phase 3 trials of adalimumab in patients with polyarticular juvenile idiopathic arthritis who were 4 to 17 years and enthesitis-related arthritis who were 6 to 17 years, ALT elevations ≥ 3 × ULN occurred in 6.1% of adalimumab-treated patients and 1.3% of control-treated patients. Most ALT elevations occurred with concomitant methotrexate use. No ALT elevations ≥ 3 × ULN occurred in the phase 3 trial of adalimumab in patients with polyarticular juvenile idiopathic arthritis who were 2 to < 4 years.

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