Wechselwirkungen · Steglujan
Steglujan 5 mg/100 mg film-coated tablets Steglujan 15 mg/100 mg film-coated tablets · Abschnitt 4.5 · PDF-Seite 8
HOS-226331 · Präparat HOS-217572
Digoxin: Sitagliptin had a small effect on plasma digoxin concentrations. Following administration of 0.25 mg digoxin concomitantly with 100 mg of sitagliptin daily for 10 days, the plasma AUC of digoxin was increased on average by 11% and the plasma Cmax on average by 18%. No dose adjustment of digoxin is recommended. However, patients at risk of digoxin toxicity should be monitored for this when sitagliptin and digoxin are administered concomitantly.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
RxNorm-Namen im Text (wörtliche Treffer, Rolle nicht bewertet): digoxin (HOS-086172) sitagliptin (HOS-117222)
Vollständigen Kontext in der EMA-Fachinformation lesen →Quellennachweis
Version 2025-11-21T12:39:00Z · SHA-256 3b4188502ad9bec96c5442d6c3519219d4a6dc9277aef13af7c65892559aabc1 · Passage 746922840c34e0fbd05fbe0a445c20212bb1c8d8a78bd3514abf4b209175a9fb · Zeichen 3865–4321 im Abschnitt