Exakte Wirkstoffkennungen und zitierbare Passagen zu Wechselwirkungen, Gegenanzeigen und Nebenwirkungen.
Ein Paarvergleich findet Originalpassagen, die den anderen Wirkstoff wörtlich nennen. Aussagen gelten für das jeweilige Präparat und seine Formulierung. Klassenbegriffe und abweichende Synonyme können fehlen. Kein Treffer bedeutet nicht, dass keine Wechselwirkung besteht.
In a study in volunteers doses of 4 mg/kg and 16 mg/kg of sugammadex resulted in maximum mean
prolongations of aPTT by 17 and 22% respectively and of PT(INR) by 11 and 22% respectively.
These limited mean aPTT and PT(INR) prolongations were of short duration (≤ 30 minutes).
In in vitro experiments a pharmacodynamic interaction (aPTT and PT prolongation) was noted with
vitamin K antagonists, unfractionated heparin, low molecular weight heparinoids, rivaroxaban and
dabigatran (see section 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
In a study in volunteers doses of 4 mg/kg and 16 mg/kg of sugammadex resulted in maximum mean
prolongations of aPTT by 17 and 22% respectively and of PT(INR) by 11 and 22% respectively.
These limited mean aPTT and PT(INR) prolongations were of short duration (≤ 30 minutes).
In in vitro experiments a pharmacodynamic interaction (aPTT and PT prolongation) was noted with
vitamin K antagonists, unfractionated heparin, low molecular weight heparinoids, rivaroxaban and
dabigatran (see section 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
In a study in volunteers doses of 4 mg/kg and 16 mg/kg of sugammadex resulted in maximum mean
prolongations of aPTT by 17 and 22% respectively and of PT(INR) by 11 and 22% respectively.
These limited mean aPTT and PT(INR) prolongations were of short duration (≤ 30 minutes).
In in vitro experiments a pharmacodynamic interaction (aPTT and PT prolongation) was noted with
vitamin K antagonists, unfractionated heparin, low molecular weight heparinoids, rivaroxaban and
dabigatran (see section 4.4).
7
Paediatric population
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
In a study in volunteers doses of 4 mg/kg and 16 mg/kg of sugammadex resulted in maximum mean
prolongations of Activated Partial Thromboplastin Time (aPTT) by 17 and 22% respectively and of
PT(INR) by 11 and 22% respectively.
These limited mean Activated Partial Thromboplastin Time(aPTT) and PT(INR) prolongations were
of short duration (≤ 30 minutes).
In in vitro experiments a pharmacodynamic interaction (Activated Partial Thromboplastin Time
(aPTT) and PT prolongation) was noted with vitamin K antagonists, unfractionated heparin, low
molecular weight heparinoids, rivaroxaban and dabigatran (see section 4.4).
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
Version 2026-01-16T17:21:00Z · SHA-256 e7be1eb58d32faccb389767c0e9e5884057016dec53c72705ce1121f897cfb97 · Passage 764d992476182735fa4bec79c4f28b972117f5ee70d03e51f3e84e09c987a77f · Zeichen 4910–5526 im Abschnitt
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