Exakte Wirkstoffkennungen und zitierbare Passagen zu Wechselwirkungen, Gegenanzeigen und Nebenwirkungen.
Ein Paarvergleich findet Originalpassagen, die den anderen Wirkstoff wörtlich nennen. Aussagen gelten für das jeweilige Präparat und seine Formulierung. Klassenbegriffe und abweichende Synonyme können fehlen. Kein Treffer bedeutet nicht, dass keine Wechselwirkung besteht.
Medicinal products metabolised by CYP2B6, UGT1A1 or transported by BCRP or OATP2B1
Letermovir is a general inducer in vivo but has also been observed to inhibit CYP2B6, UGT1A1,
BCRP, and OATP2B1 in vitro. The net effect in vivo is unknown. Therefore, the plasma
concentrations of medicinal products that are substrates of these enzymes or transporters may increase
or decrease when co-administered with letermovir. Additional monitoring may be recommended; refer
to the prescribing information for such medicinal products.
- Examples of medicinal products that are metabolised by CYP2B6 include bupropion.
- Examples of medicinal products metabolised by UGT1A1 are raltegravir and dolutegravir.
- Examples of medicinal products transported by BCRP include rosuvastatin and sulfasalazine.
- An example of a medicinal product transported by OATP2B1 is celiprolol.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
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-Examples of medicinal products metabolised by UGT1A1 are raltegravir and dolutegravir.
-Examples of medicinal products transported by BCRP include rosuvastatin and sulfasalazine.
-An example of a medicinal product transported by OATP2B1 is celiprolol.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
Medicinal products metabolised by CYP2B6, UGT1A1 or transported by BCRP or OATP2B1
Letermovir is a general inducer in vivo but has also been observed to inhibit CYP2B6, UGT1A1,
BCRP, and OATP2B1 in vitro. The net effect in vivo is unknown. Therefore, the plasma
concentrations of medicinal products that are substrates of these enzymes or transporters may increase
or decrease when co-administered with letermovir. Additional monitoring may be recommended; refer
to the prescribing information for such medicinal products.
- Examples of medicinal products that are metabolised by CYP2B6 include bupropion.
- Examples of medicinal products metabolised by UGT1A1 are raltegravir and dolutegravir.
- Examples of medicinal products transported by BCRP include rosuvastatin and sulfasalazine.
- An example of a medicinal product transported by OATP2B1 is celiprolol.
Originalpassage; keine automatisch abgeleitete Schwere, Häufigkeit oder Kausalität. Auch verneinte Befunde und nicht untersuchte Kombinationen bleiben sichtbar.
Version 2025-12-12T02:00:00Z · SHA-256 db4998a6cb590006789107af9f09c4196d815ed441a57d076042c2223b8d34a9 · Passage 7b36ebe5215851576511c9391e13a703abd6367cdc0ba12114699ad98dc3e9f9 · Zeichen 8695–9556 im Abschnitt
This product uses publicly available data from the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.