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Eintrag öffnenAutoimmun-Polyendokrinopathie Typ 1
Eintrag öffnenAxura · 4.5 · 5 In single-dose pharmacokinetic (PK) studies in young healthy subjects no relevant active substance- active s
Eintrag öffnenAxura · 4.5 · In single-dose pharmacokinetic (PK) studies in young healthy subjects no relevant active substance-active subs
Eintrag öffnenAyvakyt · 4.8 · Advanced systemic mastocytosis Cognitive effects occurred in 51 (26%) of the 193 patients with AdvSM (all dose
Eintrag öffnenAyvakyt · 4.8 · Cognitive effects occurred in 20% of the patients aged ≥65 years receiving a starting dose of 200 mg once dail
Eintrag öffnenAyvakyt · 4.8 · Cognitive effects occurred in 37% of the patients aged ≥65 years receiving a starting dose of either 300 or 40
Eintrag öffnenAyvakyt · 4.8 · Fatal events of intracranial haemorrhage have occurred in less than 1% of patients with AdvSM (all doses).
Eintrag öffnenAyvakyt · 4.8 · For patients with AdvSM treated at a starting dose of 200 mg, cognitive disorder occurred in 12% of patients,
Eintrag öffnenAyvakyt · 4.8 · Most cognitive effects were Grade 1, with Grade ≥2 occurring in 7% of 126 patients treated at a starting dose
Eintrag öffnenAyvakyt · 4.8 · Overall, 1.6% of AdvSM patients (all doses) required permanent discontinuation of avapritinib for a cognitive
Eintrag öffnenAyvakyt · 4.8 · Serious adverse reactions of cognitive effects were reported for 1 of 193 (<1%) AdvSM patients (all doses), no
Eintrag öffnenAyvakyt · 4.8 · The maximum dose for patients with AdvSM must not exceed 200 mg once daily. 16 Indolent systemic mastocytosis
Eintrag öffnenAyvakyt · 4.8 · The safety database includes a total of 585 patients with GIST (all doses), of which 550 patients received ava
Eintrag öffnenAzacitidine Accord · 4.8 · Dose interruptions due to an adverse reaction occurred in 36.4% of patients who received Azacitidine Accord. A
Eintrag öffnenAzacitidine Accord · 4.8 · Dose reductions due to an adverse reaction period occurred in 14% of patients who received Azacitidine Accord.
Eintrag öffnenAzidose
Eintrag öffnenAzidose
Eintrag öffnenAzidose, Laktat-
Eintrag öffnenAzidose, renale tubuläre
Eintrag öffnen