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Lorviqua · 4.5 · CYP2C9 substrates
Eintrag öffnenLorviqua · 4.5 · CYP3A4/5 substrates
Eintrag öffnenLorviqua · 4.5 · P-glycoprotein substrates
Eintrag öffnenLorviqua · 4.5 · UGT substrates
Eintrag öffnenLumykras · 4.5 · 7 Effect of sotorasib on P-gp substrates Co-administration of sotorasib with digoxin (a P-glycoprotein [P-gp]
Eintrag öffnenLumykras · 4.5 · Avoid co-administration of LUMYKRAS with CYP3A4 substrates with narrow therapeutic indices, including but not
Eintrag öffnenLumykras · 4.5 · BCRP substrates LUMYKRAS is a weak BCRP inhibitor. Co-administration of LUMYKRAS with a BCRP substrate led to
Eintrag öffnenLumykras · 4.5 · CYP2B6, CYP2C8, CYP2C9 and CYP2C19 substrates In vitro data indicated that sotorasib may have the potential to
Eintrag öffnenLumykras · 4.5 · CYP2D6 substrates In vitro data indicated that sotorasib may have the potential to inhibit CYP2D6, the clinica
Eintrag öffnenLumykras · 4.5 · CYP3A4 substrates Sotorasib is a moderate CYP3A4 inducer. Co-administration of sotorasib with CYP3A4 substrate
Eintrag öffnenLunsumio · 4.5 · A transient clinically relevant effect on CYP450 substrates with a narrow therapeutic index (e.g. warfarin, vo
Eintrag öffnenLunsumio · 4.5 · A transient clinically relevant effect on CYP450 substrates with a narrow therapeutic index (e.g. warfarin, vo
Eintrag öffnenLupkynis · 4.5 · BCRP substrates Voclosporin inhibits breast cancer resistance protein (BCRP) in vitro. A clinically relevant i
Eintrag öffnenLupkynis · 4.5 · CYP3A4 substrates Multiple administrations of voclosporin orally (0.4 mg/kg twice daily) had no clinically rel
Eintrag öffnenLupkynis · 4.5 · OATP1B1/OATP1B3 substrates Voclosporin is an inhibitor of OATP1B1 and OATP1B3 transporters. In one clinical st
Eintrag öffnenLupkynis · 4.5 · P-gp substrates Voclosporin is an inhibitor of P-glycoprotein (P-gp). Concomitant administration of voclospori
Eintrag öffnenLynozyfic · 4.5 · 14 products that are CYP substrates where minimal changes in concentration may lead to serious adverse reactio
Eintrag öffnenLytgobi · 4.5 · 6 Effect of futibatinib on BCRP substrates Rosuvastatin (a sensitive BCRP substrate) geometric mean ratios for
Eintrag öffnenLytgobi · 4.5 · Effect of futibatinib on CYP1A2 substrates In vitro studies indicate that futibatinib has the potential to ind
Eintrag öffnenLytgobi · 4.5 · Effect of futibatinib on P-gp substrates Digoxin (a sensitive P-gp substrate) geometric mean ratios for Cmax a
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