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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Aptivus“
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Aptivus · 4.5 · 19 H2-receptor antagonists No interaction study No data are available for An increase in gastric pH that perfo
Eintrag öffnenAptivus · 4.5 · 20 Antipsychotics Pimozide Based on theoretical The concomitant use of Aptivus, Sertindole considerations, tip
Eintrag öffnenAptivus · 4.5 · 21 CYP 3A4 inhibition by tipranavir/r Others Theophylline Based on data from the cocktail Theophylline plasma
Eintrag öffnenAptivus · 4.5 · 22 Bupropion 150 mg BID Bupropion Cmax ↓ 51% If the co-administration with Bupropion AUC ↓ 56% bupropion is ju
Eintrag öffnenAptivus · 4.5 · 8 In vitro studies show that tipranavir is a substrate and also an inhibitor of P-gp.
Eintrag öffnenAptivus · 4.5 · 9 Drugs by therapeutic area Interaction Recommendations concerning Geometric mean change (%) co-administration
Eintrag öffnenAptivus · 4.5 · A cocktail study was conducted in 16 healthy volunteers with twice-daily 500 mg tipranavir with 200 mg ritonav
Eintrag öffnenAptivus · 4.5 · Abacavir 300 mg BID Abacavir Cmax ↓ 46% The concomitant use of Aptivus, (TPV/r 750/100 mg BID) Abacavir AUC ↓
Eintrag öffnenAptivus · 4.5 · Antacids aluminium- and Tipranavir Cmax ↓ 25% Dosing of Aptivus, co- magnesium-based antacid Tipranavir AUC ↓
Eintrag öffnenAptivus · 4.5 · Anti-infectives Antiretrovirals Nucleoside and nucleotide reverse transcriptase inhibitors (NRTIs) Since there
Eintrag öffnenAptivus · 4.5 · Based on theoretical considerations, tipranavir or ritonavir concentrations might increase upon co-administrat
Eintrag öffnenAptivus · 4.5 · Carbamazepine induces CYP3A4. Phenobarbital Phenobarbital and phenytoin Phenobarbital and phenytoin Phenytoin
Eintrag öffnenAptivus · 4.5 · Co-administration of Aptivus and agents that induce CYP3A and/or P-gp may decrease tipranavir concentrations a
Eintrag öffnenAptivus · 4.5 · Colchicine is a substrate of CYP3A4 and P-gp (an intestinal efflux transporter). Antibiotics Clarithromycin 50
Eintrag öffnenAptivus · 4.5 · Concomitant use of Aptivus/ritonavir caused a decrease of etravirine exposure that could significantly impair
Eintrag öffnenAptivus · 4.5 · Digoxin 0.25 mg QD po First-dose tipranavir/r Digoxin Cmax ↑ 93% Digoxin AUC ↑ 91%
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 2D6 by tipranavir/r Antihistamines Astemizole Based on theoretical The concomitant use of Ap
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 2D6 by tipranavir/r Digoxin 0.25 mg QD iv First-dose tipranavir/r Monitoring of digoxin seru
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 3A4 and CYP 2D6 by tipranavir/r Endothelin receptor antagonists Bosentan Based on theoretica
Eintrag öffnenAptivus · 4.5 · Inhibition of CYP 3A4 by tipranavir/r. Oral contraceptives / Oestrogens Ethinyl oestradiol Ethinyl oestradiol
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