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Avzivi · 4.8 · 15 Uncommon (≥ 0.1% to < 1%) reports of fistulae that involve areas of the body other than the gastrointestina
Eintrag öffnenAvzivi · 4.8 · 16 clinical presentation of PRES is often nonspecific, and therefore the diagnosis of PRES requires confirmati
Eintrag öffnenAvzivi · 4.8 · 17 Tumour-associated haemorrhage was also seen rarely in other tumour types and locations, including cases of
Eintrag öffnenAvzivi · 4.8 · 18 with bevacizumab in combination with paclitaxel and cisplatin compared with up to 7.0% of patients treated
Eintrag öffnenAvzivi · 4.8 · 19 of bevacizumab treatment, ovarian function recovered in 86.2% of these evaluable women. Long term effects o
Eintrag öffnenAvzivi · 4.8 · 20 Infestations gastrointestinal perforation or fistula formation (rare) (see also section 4.4) Immune system
Eintrag öffnenAvzivi · 4.8 · Across all clinical trials, mucocutaneous haemorrhage has been seen in up to 50% of bevacizumab- treated patie
Eintrag öffnenAvzivi · 4.8 · Across clinical trials, 8 cases of PRES have been reported. Two of the eight cases did not have radiological c
Eintrag öffnenAvzivi · 4.8 · Across clinical trials, the following Grade 3 and 4 (NCI-CTCAE v.3) laboratory abnormalities occurred in patie
Eintrag öffnenAvzivi · 4.8 · Adverse reactions are added to the appropriate frequency category in the tables below according to the highest
Eintrag öffnenAvzivi · 4.8 · An increased incidence of CHF has been observed in a clinical trial of patients with diffuse large B-cell lymp
Eintrag öffnenAvzivi · 4.8 · Analyses of the clinical safety data suggest that the occurrence of hypertension and proteinuria with bevacizu
Eintrag öffnenAvzivi · 4.8 · Bevacizumab is not approved for use in patients under the age of 18 years. In published literature reports, ca
Eintrag öffnenAvzivi · 4.8 · Clinical trials have shown that transient increases in serum creatinine (ranging between 1.5-1.9 times baselin
Eintrag öffnenAvzivi · 4.8 · Congestive heart failure (CHF) In clinical trials with bevacizumab, congestive heart failure (CHF) was observe
Eintrag öffnenAvzivi · 4.8 · Description of selected serious adverse reactions Gastrointestinal (GI) perforations and fistulae (see section
Eintrag öffnenAvzivi · 4.8 · Fatal outcome was reported in approximately a third of serious cases of gastrointestinal perforations, which r
Eintrag öffnenAvzivi · 4.8 · From a clinical trial in patients with persistent, recurrent, or metastatic cervical cancer (GOG-240), 1.8% of
Eintrag öffnenAvzivi · 4.8 · From a clinical trial in patients with persistent, recurrent, or metastatic cervical cancer (study GOG- 0240),
Eintrag öffnenAvzivi · 4.8 · From a clinical trial in patients with persistent, recurrent, or metastatic cervical cancer (study GOG- 0240),
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