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Camzyos · 4.5 · Strong CYP2C19 plus strong CYP3A4 inhibitors Co-administration of mavacamten with the combination of a strong
Eintrag öffnenCamzyos · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenCamzyos · 4.8 Undesirable effects · 1
Eintrag öffnenCamzyos · 4.8 · 14 The adverse reactions included in table 3 are listed according to system organ class in MedDRA. Within each
Eintrag öffnenCamzyos · 4.8 · Adverse reactions reported in patients treated with mavacamten in two phase 3 studies (EXPLORER- HCM and VALOR
Eintrag öffnenCamzyos · 4.8 · Description of selected adverse reactions
Eintrag öffnenCamzyos · 4.8 · Dyspnoea In Phase 3 clinical studies, dyspnoea was reported in 12.3% of patients treated with mavacamten compa
Eintrag öffnenCamzyos · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenCamzyos · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenCamzyos · 4.8 · Summary of the safety profile
Eintrag öffnenCamzyos · 4.8 · System organ class Adverse reaction Frequency Dizziness Very common Nervous system disorders Syncope Common Ca
Eintrag öffnenCamzyos · 4.8 · Systolic dysfunction In Phase 3 clinical studies, 5% (9/179) of patients in the mavacamten group experienced r
Eintrag öffnenCamzyos · 4.8 · Table 3: Adverse reactions
Eintrag öffnenCamzyos · 4.8 · Tabulated list of adverse reactions
Eintrag öffnenCamzyos · 4.8 · The most commonly reported adverse reactions with mavacamten are dizziness (17%), dyspnoea (12%), systolic dys
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