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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Degevma“
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Degevma · 4.8 · Clinically significant hypercalcaemia after treatment discontinuation has been reported in the post-marketing
Eintrag öffnenDegevma · 4.8 · Denosumab was studied in an open-label trial that enrolled 28 skeletally mature adolescents with giant cell tu
Eintrag öffnenDegevma · 4.8 · Drug related hypersensitivity reactions In the post-marketing setting, events of hypersensitivity, including r
Eintrag öffnenDegevma · 4.8 · Hypocalcaemia A higher incidence of hypocalcaemia among patients treated with denosumab compared to zoledronic
Eintrag öffnenDegevma · 4.8 · Hypocalcaemia has very commonly been reported following denosumab administration, mostly within the first 2 we
Eintrag öffnenDegevma · 4.8 · In a long-term phase II open-label clinical trial in patients with giant cell tumour of bone (study 6, see sec
Eintrag öffnenDegevma · 4.8 · In a phase III trial in patients with non-metastatic prostate cancer (a patient population for which Degevma i
Eintrag öffnenDegevma · 4.8 · In patients with giant cell tumour of bone, incidence of new malignancy, including malignancies involving the
Eintrag öffnenDegevma · 4.8 · In the clinical trial programme for GCTB, atypical femoral fractures have been reported commonly in patients t
Eintrag öffnenDegevma · 4.8 · In the post-marketing setting, severe symptomatic hypocalcaemia (including fatal cases) has been reported, wit
Eintrag öffnenDegevma · 4.8 · In the primary treatment phases of three phase III active-controlled clinical trials in patients with advanced
Eintrag öffnenDegevma · 4.8 · In three phase III active-controlled clinical trials in patients with advanced malignancies involving bone, hy
Eintrag öffnenDegevma · 4.8 · In two phase II single-arm clinical trials in patients with giant cell tumour of bone, hypocalcaemia was repor
Eintrag öffnenDegevma · 4.8 · Lichenoid drug eruptions Lichenoid drug eruptions (e.g. lichen planus-like reactions), have been reported in p
Eintrag öffnenDegevma · 4.8 · Musculoskeletal pain In the post-marketing setting, musculoskeletal pain, including severe cases, has been rep
Eintrag öffnenDegevma · 4.8 · No treatment-related pattern in individual cancers or cancer groupings was apparent.
Eintrag öffnenDegevma · 4.8 · Osteonecrosis of the jaw (ONJ) In clinical trials, the incidence of ONJ was higher with longer duration of exp
Eintrag öffnenDegevma · 4.8 · Other special populations
Eintrag öffnenDegevma · 4.8 · Overall safety profile is consistent in all approved indications for Degevma.
Eintrag öffnenDegevma · 4.8 · Paediatric population
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