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Clopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Less pronounced reductions of metabolite exposure has been observed with pantoprazole or lansoprazole. The pla
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Medicinal products associated with bleeding risk There is an increased risk of bleeding due to the potential a
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Medicinal products that are strong or moderate CYP2C19 inhibitors include, for example, omeprazole and esomepr
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Metamizole Metamizole may reduce the effect of ASA on platelet aggregation when taken concomitantly. Therefore
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Methotrexate Due to the presence of ASA, methotrexate used at doses higher than 20 mg/week should be used with
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · NSAIDs In a clinical study conducted in healthy volunteers, the concomitant administration of clopidogrel and
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Nicorandil In patients concomitantly receiving nicorandil and NSAIDs including ASA and LAS, there is an increa
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Oral anticoagulants The concomitant administration of Clopidogrel/Acetylsalicylic acid Zentiva with oral antic
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Other concomitant therapy with ASA Interactions with the following medicinal products have been reported with
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Other interactions with ASA Interactions with the following medicinal products with higher (anti-inflammatory)
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Other interactions with clopidogrel and ASA More than 30,000 patients entered into clinical trials with clopid
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Other medicinal products A number of other clinical studies have been conducted with clopidogrel and other con
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Proton Pump Inhibitors (PPI) Omeprazole 80 mg once daily administered either at the same time as clopidogrel o
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · SSRIs Since SSRIs affect platelet activation and increase the risk of bleeding, the concomitant administration
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Tenofovir Concomitant administration of tenofovir disoproxil fumarate and NSAIDs may increase the risk of rena
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · The pharmacokinetics of digoxin or theophylline were not modified by the co-administration of clopidogrel. Ant
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · There is no evidence that other medicinal products that reduce stomach acid such as H2 blockers or antacids in
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Thrombolytics The safety of the concomitant administration of clopidogrel, fibrin or non-fibrin specific throm
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Uricosurics (benzbromarone, probenecid, sulfinpyrazone)
Eintrag öffnenClopidogrel/Acetylsalicylic acid Zentiva (previously DuoCover) · 4.5 · Valproic acid The concomitant administration of salicylates and valproic acid may result in decreased valproic
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