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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Edurant“
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Edurant · 4.5 · (inhibition of CYP3A enzymes) Fluconazole Not studied. Concomitant use of No dose adjustment is required. Itra
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) GLUCOCORTICOIDS Dexamethasone Not studied. Dose dependent Rilpivirine should not
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) GLUCOCORTICOIDS Dexamethasone Not studied. Dose dependent Rilpivirine should not
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) Lopinavir/ritonavir lopinavir AUC ↔ (soft gel capsule)*# lopinavir Cmin ↓ 11% 40
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) Lopinavir/ritonavir lopinavir AUC ↔ (soft gel capsule)*# lopinavir Cmin ↓ 11% 40
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) Other boosted PIs Not studied. (atazanavir/ritonavir, fosamprenavir/ritonavir, s
Eintrag öffnenEdurant · 4.5 · (inhibition of CYP3A enzymes) Other boosted PIs Not studied. (atazanavir/ritonavir, fosamprenavir/ritonavir, s
Eintrag öffnenEdurant · 4.5 · (inhibition of intestinal P-gp) ANTIDIABETICS Metformin* metformin AUC ↔ No dose adjustment is required. 850 m
Eintrag öffnenEdurant · 4.5 · (inhibition of intestinal P-gp) ANTIDIABETICS Metformin* metformin AUC ↔ No dose adjustment is required. 850 m
Eintrag öffnenEdurant · 4.5 · (reduced absorption due to gastric pH increase) Lansoprazole Not studied. Significant decreases Rabeprazole in
Eintrag öffnenEdurant · 4.5 · (reduced absorption due to gastric pH increase) Lansoprazole Not studied. Significant decreases Rabeprazole in
Eintrag öffnenEdurant · 4.5 · * compared to 25 mg once daily rilpivirine alone
Eintrag öffnenEdurant · 4.5 · 28 Interactions between rilpivirine and co-administered medicinal products are listed in Table 2(increase is i
Eintrag öffnenEdurant · 4.5 · 29 HIV Integrase Strand Transfer Inhibitors Raltegravir* raltegravir AUC ↑ 9% No dose adjustment is required.
Eintrag öffnenEdurant · 4.5 · 30 MACROLIDE ANTIBIOTICS Clarithromycin Not studied. Increased exposure of Where possible, alternatives such a
Eintrag öffnenEdurant · 4.5 · 300 mg once daily rilpivirine AUC ↑ 16%* (+ 50 mg once daily rilpivirine Cmin ↔* rilpivirine) rilpivirine Cmax
Eintrag öffnenEdurant · 4.5 · 31 NARCOTIC ANALGESICS Methadone* R(-) methadone AUC ↓ 16% No dose adjustments are required 60-100 mg once dai
Eintrag öffnenEdurant · 4.5 · 32 * The interaction between rilpivirine and the medicinal product was evaluated in a clinical study. All othe
Eintrag öffnenEdurant · 4.5 · 5 Table 1: INTERACTIONS AND DOSE RECOMMENDATIONS WITH OTHER MEDICINAL PRODUCTS Medicinal products by Interacti
Eintrag öffnenEdurant · 4.5 · 6 HIV Integrase Strand Transfer Inhibitors Raltegravir* raltegravir AUC ↑ 9% No dose adjustment is required. r
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