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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Epidyolex“
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Epidyolex · 4.5 · Sensitive P-gp substrates given orally Coadministration of cannabidiol with orally administered everolimus, a
Eintrag öffnenEpidyolex · 4.5 · Sensitive UGT1A9 substrates Coadministration of cannabidiol (7.5 mg/kg twice daily) with a single dose of myco
Eintrag öffnenEpidyolex · 4.5 · Sensitive UGT2B7 substrates Coadministration of cannabidiol (7.5 mg/kg twice daily) with a single dose of zido
Eintrag öffnenEpidyolex · 4.5 · Sensitive substrates of CYP1A2, CYP2B6, CYP2C8, CYP2C9, CYP2C19, UGT1A9, and UGT2B7 Sensitive CYP1A2 substrate
Eintrag öffnenEpidyolex · 4.5 · Stiripentol When cannabidiol was combined with stiripentol in a healthy volunteer trial there was an increase
Eintrag öffnenEpidyolex · 4.5 · The pharmacokinetics of cannabidiol are complex and may cause interactions with the patient’s concomitant AED
Eintrag öffnenEpidyolex · 4.5 · The potential for drug-drug interactions with other concomitant AEDs has been assessed in healthy volunteers a
Eintrag öffnenEpidyolex · 4.5 · The strong CYP3A4/2C19 inducing agent rifampicin (600 mg administered once daily) decreased plasma concentrati
Eintrag öffnenEpidyolex · 4.5 · UGT inhibitors
Eintrag öffnenEpidyolex · 4.5 · Valproate Concomitant use of cannabidiol and valproate increases the incidence of transaminase enzyme elevatio
Eintrag öffnenEpidyolex · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenEpidyolex · 4.8 Undesirable effects · 1
Eintrag öffnenEpidyolex · 4.8 · 10 Table 3: Tabulated list of adverse reactions System Organ Class Frequency Adverse reactions from clinical t
Eintrag öffnenEpidyolex · 4.8 · 11 The risk of ALT elevations was higher at doses higher than the 25 mg/kg/day in the controlled study in TSC.
Eintrag öffnenEpidyolex · 4.8 · 12 during the course of the study (defined as a normal haemoglobin concentration at baseline, with a reported
Eintrag öffnenEpidyolex · 4.8 · Adverse reactions reported with cannabidiol in placebo-controlled clinical studies are listed in the table bel
Eintrag öffnenEpidyolex · 4.8 · Adverse reactions reported with cannabidiol in the recommended dose range of 10 to 25 mg/kg/day are shown belo
Eintrag öffnenEpidyolex · 4.8 · Baseline transaminase elevations In controlled trials (see section 5.1) in patients taking cannabidiol 20 or 2
Eintrag öffnenEpidyolex · 4.8 · Concomitant valproate and clobazam In cannabidiol-treated patients receiving doses of 10, 20, and 25 mg/kg/day
Eintrag öffnenEpidyolex · 4.8 · Decreased weight Cannabidiol can cause weight loss or decreased weight gain (see section 4.4). In LGS, DS and
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