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Etcamah · 4.5 · P-gp sensitive substrates In vitro data show that camizestrant is an inhibitor of P-glycoprotein (P-gp). There
Eintrag öffnenEtcamah · 4.5 · The co-administration of camizestrant and moderately sensitive substrates of CYP2C9 (including but not limited
Eintrag öffnenEtcamah · 4.5 · When co-administering camizestrant in combination with ribociclib, plus a moderate CYP3A4/5 inducer (including
Eintrag öffnenEtcamah · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenEtcamah · 4.8 Undesirable effects · 1
Eintrag öffnenEtcamah · 4.8 · 10 nadir at approximately 14 days and generally recovered following treatment cessation in a similar time cour
Eintrag öffnenEtcamah · 4.8 · 8 Table 2 Adverse drug reactions reported in the Etcamah and CDK4/6 inhibitor combination (n = 263) a MedDRA S
Eintrag öffnenEtcamah · 4.8 · 9 Vomitinge,f,g Very common Uncommon
Eintrag öffnenEtcamah · 4.8 · Abdominal paing Common Common
Eintrag öffnenEtcamah · 4.8 · Adverse drug reactions identified for Etcamah in the Etcamah and CDK4/6 inhibitors combination are visual effe
Eintrag öffnenEtcamah · 4.8 · Adverse reactions are listed by MedDRA System Organ Class (SOC) and by descending frequency of the MedDRA grou
Eintrag öffnenEtcamah · 4.8 · Adverse reactions leading to treatment discontinuation of Etcamah in patients receiving Etcamah in combination
Eintrag öffnenEtcamah · 4.8 · Alanine Common Common aminotransferase increasede,f,g
Eintrag öffnenEtcamah · 4.8 · Blood and lymphatic Neutropenia e,f,g,h Very common Very common system disorders Anaemiae,f,g,i Very common Co
Eintrag öffnenEtcamah · 4.8 · Blood creatinine Common - increasede,g
Eintrag öffnenEtcamah · 4.8 · Bradycardia Among the 19.8% patients with bradycardia reported, 85% patients had bradycardia reported as asymp
Eintrag öffnenEtcamah · 4.8 · Bradycardia in the presence of drug-induced QTc prolongation has the potential to increase the risk of arrhyth
Eintrag öffnenEtcamah · 4.8 · Cardiac disorders Bradycardiac Very common -
Eintrag öffnenEtcamah · 4.8 · Constipationg Common -
Eintrag öffnenEtcamah · 4.8 · Description of selected adverse reaction
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