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Evista · 4.5 · Raloxifene should not be co-administered with cholestyramine (or other anion exchange resins), which significa
Eintrag öffnenEvista · 4.5 · The influence of concomitant medication on raloxifene plasma concentrations was evaluated in the prevention an
Eintrag öffnenEvista · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenEvista · 4.8 Undesirable effects · 1
Eintrag öffnenEvista · 4.8 · 5 The following convention has been used for the classification of the adverse reactions: very common (≥1/10),
Eintrag öffnenEvista · 4.8 · 6 In the RUTH study, raloxifene did not affect the incidence of stroke, compared to placebo. However, there wa
Eintrag öffnenEvista · 4.8 · Across all placebo-controlled clinical trials of raloxifene in osteoporosis, venous thromboembolic events, inc
Eintrag öffnenEvista · 4.8 · Another adverse reaction observed was leg cramps (5.5 % for Evista, 1.9 % for placebo in the prevention popula
Eintrag öffnenEvista · 4.8 · Blood and lymphatic system disorders Uncommon: Thrombocytopenia a Nervous system disorders Common: Headache, i
Eintrag öffnenEvista · 4.8 · Evista (n = 317) was compared with continuous combined (n = 110) hormone replacement therapy (HRT) or cyclic (
Eintrag öffnenEvista · 4.8 · Flu syndrome was reported by 16.2 % of Evista treated patients and 14.0 % of placebo treated patients.
Eintrag öffnenEvista · 4.8 · In a study of 10,101 postmenopausal women with documented coronary heart disease or at increased risk for coro
Eintrag öffnenEvista · 4.8 · In the RUTH study, venous thromboembolic events occurred at a frequency of approximately 2.0 % or 3.88 cases p
Eintrag öffnenEvista · 4.8 · In the prevention population discontinuations of therapy due to any adverse reaction occurred in 10.7 % of 581
Eintrag öffnenEvista · 4.8 · One further change was seen which was not statistically significant (p 0.05), but which did show a significa
Eintrag öffnenEvista · 4.8 · Rare cases of moderate increases in AST and/or ALT have been reported where a causal relationship to raloxifen
Eintrag öffnenEvista · 4.8 · Reporting of suspected adverse reactions Reporting suspected adverse reactions after authorisation of the medi
Eintrag öffnenEvista · 4.8 · The frequencies for postmarketing reports were calculated from placebo-controlled clinical trials (comprising
Eintrag öffnenEvista · 4.8 · a. Summary of the safety profile The clinically most important adverse reactions reported in postmenopausal wo
Eintrag öffnenEvista · 4.8 · b. Tabulated summary of adverse reactions The table below gives the adverse reactions and frequencies observed
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