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Forxiga · 4.5 · Paediatric population
Eintrag öffnenForxiga · 4.5 · Pharmacodynamic interactions
Eintrag öffnenForxiga · 4.5 · The metabolism of dapagliflozin is primarily via glucuronide conjugation mediated by UDP glucuronosyltransfera
Eintrag öffnenForxiga · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenForxiga · 4.8 Undesirable effects · 1
Eintrag öffnenForxiga · 4.8 · 11 In the DECLARE study, the numbers of patients with events suggestive of volume depletion were balanced betw
Eintrag öffnenForxiga · 4.8 · 12 In the DAPA-CKD study, the numbers of patients with serious adverse events of urinary tract infections were
Eintrag öffnenForxiga · 4.8 · 8 exposure time of 27 months. The patient population included patients with type 2 diabetes mellitus and witho
Eintrag öffnenForxiga · 4.8 · 9 System organ Very common Common* Uncommon** Rare Very rare class Weight decreased** a The table shows up to
Eintrag öffnenForxiga · 4.8 · Chronic kidney disease In the dapagliflozin renal outcome study in patients with chronic kidney disease (DAPA-
Eintrag öffnenForxiga · 4.8 · Description of selected adverse reactions
Eintrag öffnenForxiga · 4.8 · Diabetic ketoacidosis in type 2 diabetes mellitus In the DECLARE study, with a median exposure time of 48 mont
Eintrag öffnenForxiga · 4.8 · For studies of dapagliflozin in monotherapy, as add-on to metformin or as add-on to sitagliptin (with or witho
Eintrag öffnenForxiga · 4.8 · Further evaluation of patients who had renal-related adverse events showed that most had serum creatinine chan
Eintrag öffnenForxiga · 4.8 · Heart failure In the dapagliflozin cardiovascular outcome study in patients with heart failure with reduced ej
Eintrag öffnenForxiga · 4.8 · Hypoglycaemia The frequency of hypoglycaemia depended on the type of background therapy used in the clinical s
Eintrag öffnenForxiga · 4.8 · In an add-on to glimepiride study, at weeks 24 and 48, minor episodes of hypoglycaemia were reported more freq
Eintrag öffnenForxiga · 4.8 · In an add-on to insulin study, episodes of major hypoglycaemia were reported in 0.5% and 1.0% of subjects trea
Eintrag öffnenForxiga · 4.8 · In an add-on to metformin and a sulphonylurea study, up to 24 weeks, no episodes of major hypoglycaemia were r
Eintrag öffnenForxiga · 4.8 · In the DAPA-CKD study, eGFR decreased over time in both the dapagliflozin group and the placebo group. The ini
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