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Glivec · 4.8 Undesirable effects · 1
Eintrag öffnenGlivec · 4.8 · 12 When imatinib was combined with high dose chemotherapy in Ph+ ALL patients, transient liver toxicity in the
Eintrag öffnenGlivec · 4.8 · 13 Nervous system disorders Very common: Headache2 Common: Dizziness, paraesthesia, taste disturbance, hypoaes
Eintrag öffnenGlivec · 4.8 · 14 Skin and subcutaneous tissue disorders Very common: Periorbital oedema, dermatitis/eczema/rash Common: Prur
Eintrag öffnenGlivec · 4.8 · 15 Investigations Very common: Weight increased Common: Weight decreased Uncommon: Blood creatinine increased,
Eintrag öffnenGlivec · 4.8 · 16 Biochemistry Severe elevation of transaminases (<5%) or bilirubin (<1%) was seen in CML patients and was us
Eintrag öffnenGlivec · 4.8 · Adverse reactions
Eintrag öffnenGlivec · 4.8 · Adverse reactions and their frequencies are reported in Table 1.
Eintrag öffnenGlivec · 4.8 · Adverse reactions reported as more than an isolated case are listed below, by system organ class and by freque
Eintrag öffnenGlivec · 4.8 · Description of selected adverse reactions
Eintrag öffnenGlivec · 4.8 · Haematology In CML, cytopenias, particularly neutropenia and thrombocytopenia, have been a consistent finding
Eintrag öffnenGlivec · 4.8 · Hepatitis B reactivation Hepatitis B reactivation has been reported in association with BCR-ABL TKIs. Some cas
Eintrag öffnenGlivec · 4.8 · In clinical trials in CML, drug discontinuation for drug-related adverse reactions was observed in 2.4% of new
Eintrag öffnenGlivec · 4.8 · In the study in patients with unresectable and/or metastatic GIST, grade 3 and 4 anaemia was reported in 5.4%
Eintrag öffnenGlivec · 4.8 · Infections and infestations Uncommon: Herpes zoster, herpes simplex, nasopharyngitis, pneumonia1, sinusitis, c
Eintrag öffnenGlivec · 4.8 · Laboratory test abnormalities
Eintrag öffnenGlivec · 4.8 · Miscellaneous adverse reactions such as pleural effusion, ascites, pulmonary oedema and rapid weight gain with
Eintrag öffnenGlivec · 4.8 · Patients with advanced stages of malignancies may have numerous confounding medical conditions that make causa
Eintrag öffnenGlivec · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenGlivec · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
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