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Herwenda · 4.8 · 13 System organ class Adverse reaction Frequency Pyrexia Very common Mucosal inflammation Very common Peripher
Eintrag öffnenHerwenda · 4.8 · 14 fever, dyspnoea, hypotension, wheezing, bronchospasm, tachycardia, reduced oxygen saturation, respiratory d
Eintrag öffnenHerwenda · 4.8 · All the terms included are based on the highest percentage seen in pivotal clinical studies. In addition, term
Eintrag öffnenHerwenda · 4.8 · Amongst the most serious and/or common adverse reactions reported in trastuzumab usage (intravenous and subcut
Eintrag öffnenHerwenda · 4.8 · Anaphylactoid reactions have been observed in isolated cases.
Eintrag öffnenHerwenda · 4.8 · Cardiac dysfunction
Eintrag öffnenHerwenda · 4.8 · Congestive heart failure (NYHA class II-IV) is a common adverse reaction associated with the use of trastuzuma
Eintrag öffnenHerwenda · 4.8 · Description of selected adverse reactions
Eintrag öffnenHerwenda · 4.8 · Details of risk minimisation measures that are consistent with the EU Risk Management Plan are presented in se
Eintrag öffnenHerwenda · 4.8 · Febrile neutropenia, leukopenia, anaemia, thrombocytopenia and neutropenia occurred very commonly. The frequen
Eintrag öffnenHerwenda · 4.8 · Haematotoxicity
Eintrag öffnenHerwenda · 4.8 · Immunogenicity
Eintrag öffnenHerwenda · 4.8 · In 3 pivotal clinical studies of adjuvant trastuzumab given in combination with chemotherapy, the incidence of
Eintrag öffnenHerwenda · 4.8 · In the neoadjuvant-adjuvant EBC study (BO22227), at a median follow-up exceeding 70 months, 10.1% (30/296) of
Eintrag öffnenHerwenda · 4.8 · In the pivotal metastatic studies of intravenous trastuzumab, the incidence of cardiac dysfunction varied betw
Eintrag öffnenHerwenda · 4.8 · In this section, the following categories of frequency have been used: very common (≥ 1/10), common (≥ 1/100 t
Eintrag öffnenHerwenda · 4.8 · Infusion reactions, allergic-like reactions and hypersensitivity
Eintrag öffnenHerwenda · 4.8 · It is estimated that approximately 40% of patients who are treated with trastuzumab will experience some form
Eintrag öffnenHerwenda · 4.8 · Presented in Table 1 are adverse reactions that have been reported in association with the use of intravenous
Eintrag öffnenHerwenda · 4.8 · Pulmonary events
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