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Begriffe & Kennungen
Hycamtin · 4.5 · When combining topotecan with other chemotherapy agents, reduction of the doses of each medicinal product may
Eintrag öffnenHycamtin · 4.5 · When combining topotecan with other chemotherapy agents, reduction of the doses of each medicinal product may
Eintrag öffnenHycamtin · 4.5 · When topotecan (0.75 mg/m2/day for 5 consecutive days) and cisplatin (60 mg/m2/day on day 1) were administered
Eintrag öffnenHycamtin · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenHycamtin · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenHycamtin · 4.8 Undesirable effects · 1
Eintrag öffnenHycamtin · 4.8 Undesirable effects · 2
Eintrag öffnenHycamtin · 4.8 · 20 Not known Mucosal inflammation 1 Fatalities due to sepsis have been reported in patients treated with topot
Eintrag öffnenHycamtin · 4.8 · 21 Reporting of suspected adverse reactions
Eintrag öffnenHycamtin · 4.8 · 6 Immune system disorders Common Hypersensitivity reaction including rash Rare Anaphylactic reaction, angioede
Eintrag öffnenHycamtin · 4.8 · 7 Non-haematological
Eintrag öffnenHycamtin · 4.8 · Additional adverse events were seen when topotecan was given in combination with cisplatin; however, these eve
Eintrag öffnenHycamtin · 4.8 · Adverse reactions are listed below, by system organ class and absolute frequency (all reported events). Freque
Eintrag öffnenHycamtin · 4.8 · Adverse reactions are listed below, by system organ class and absolute frequency (all reported events). Freque
Eintrag öffnenHycamtin · 4.8 · Anaemia Moderate to severe (Hb 8.0 g/dl) in 37% of patients (14% of courses). Red cell transfusions were give
Eintrag öffnenHycamtin · 4.8 · Anaemia Moderate to severe anaemia (Grade 3 and 4 – Hb 8.0 g/dl) occurred in 25% of patients (12% of courses)
Eintrag öffnenHycamtin · 4.8 · Complete alopecia related/possibly related to topotecan administration was observed in 9% of patients and part
Eintrag öffnenHycamtin · 4.8 · Fatigue was observed in approximately 25% and asthenia in 16% of patients receiving topotecan. Severe (Grade 3
Eintrag öffnenHycamtin · 4.8 · Frequently reported non-haematological effects were gastrointestinal, such as nausea (52%), vomiting (32%), di
Eintrag öffnenHycamtin · 4.8 · Haematological
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