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Iclusig · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenIclusig · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenIclusig · 4.5 · Substances that may decrease ponatinib serum concentrations
Eintrag öffnenIclusig · 4.5 · Substances that may decrease ponatinib serum concentrations
Eintrag öffnenIclusig · 4.5 · Substances that may have their serum concentrations altered by ponatinib
Eintrag öffnenIclusig · 4.5 · Substances that may have their serum concentrations altered by ponatinib
Eintrag öffnenIclusig · 4.5 · Substances that may increase ponatinib serum concentrations
Eintrag öffnenIclusig · 4.5 · Substances that may increase ponatinib serum concentrations
Eintrag öffnenIclusig · 4.5 · Transporter substrates In vitro, ponatinib is an inhibitor of P-gp and BCRP. Therefore, ponatinib may have the
Eintrag öffnenIclusig · 4.5 · Transporter substrates In vitro, ponatinib is an inhibitor of P-gp and BCRP. Therefore, ponatinib may have the
Eintrag öffnenIclusig · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenIclusig · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenIclusig · 4.8 Undesirable effects · 1
Eintrag öffnenIclusig · 4.8 Undesirable effects · 2
Eintrag öffnenIclusig · 4.8 · 16 occlusive disease (3.8%), anaemia (3.8%), angina pectoris (3.3%), platelet count decreased (3.1%), febrile
Eintrag öffnenIclusig · 4.8 · 17 Patients with newly diagnosed Ph+ ALL (PhALLCON Study) Myelosuppression events were reported in 83 % of pon
Eintrag öffnenIclusig · 4.8 · 18 System organ class Frequency Adverse reactions Decreased appetite Very common Hypertriglyceridaemia Hyperch
Eintrag öffnenIclusig · 4.8 · 19 System organ class Frequency Adverse reactions Cardiac failure Myocardial infarction Cardiac failure conges
Eintrag öffnenIclusig · 4.8 · 20 System organ class Frequency Adverse reactions Dyspnoea Very common Cough Pulmonary embolism Pleural effusi
Eintrag öffnenIclusig · 4.8 · 21 System organ class Frequency Adverse reactions Rash pruritic Exfoliative rash Erythema Alopecia Skin exfoli
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