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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Imbruvica“
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Imbruvica · 4.5 · Co-administration of grapefruit juice, containing CYP3A4 inhibitors, in eight healthy subjects, increased expo
Eintrag öffnenImbruvica · 4.5 · Co-administration of rifampicin, a strong CYP3A4 inducer, in 18 fasted healthy subjects, decreased exposure (C
Eintrag öffnenImbruvica · 4.5 · Co-administration of rifampicin, a strong CYP3A4 inducer, in 18 fasted healthy subjects, decreased exposure (C
Eintrag öffnenImbruvica · 4.5 · Ibrutinib has a pH dependent solubility, with lower solubility at higher pH. A lower Cmax was observed in fast
Eintrag öffnenImbruvica · 4.5 · Ibrutinib has a pH dependent solubility, with lower solubility at higher pH. A lower Cmax was observed in fast
Eintrag öffnenImbruvica · 4.5 · Ibrutinib is primarily metabolised by cytochrome P450 enzyme 3A4 (CYP3A4).
Eintrag öffnenImbruvica · 4.5 · Ibrutinib is primarily metabolised by cytochrome P450 enzyme 3A4 (CYP3A4).
Eintrag öffnenImbruvica · 4.5 · In a drug interaction study in patients with B-cell malignancies, a single 560 mg dose of ibrutinib did not ha
Eintrag öffnenImbruvica · 4.5 · In a drug interaction study in patients with B-cell malignancies, a single 560 mg dose of ibrutinib did not ha
Eintrag öffnenImbruvica · 4.5 · In studies of ibrutinib (420 mg) in combination with venetoclax (400 mg) in CLL patients, an increase in venet
Eintrag öffnenImbruvica · 4.5 · In studies of ibrutinib (420 mg) in combination with venetoclax (400 mg) in CLL patients, an increase in venet
Eintrag öffnenImbruvica · 4.5 · Mild CYP3A4 inhibitors Simulations using fasted conditions suggested that the mild CYP3A4 inhibitors azithromy
Eintrag öffnenImbruvica · 4.5 · Mild CYP3A4 inhibitors Simulations using fasted conditions suggested that the mild CYP3A4 inhibitors azithromy
Eintrag öffnenImbruvica · 4.5 · Moderate CYP3A4 inhibitors In patients with B-cell malignancies taking IMBRUVICA with food, co-administration
Eintrag öffnenImbruvica · 4.5 · Moderate CYP3A4 inhibitors In patients with B-cell malignancies taking IMBRUVICA with food, co-administration
Eintrag öffnenImbruvica · 4.5 · Strong CYP3A4 inhibitors Co-administration of ketoconazole, a very strong CYP3A4 inhibitor, in 18 fasted healt
Eintrag öffnenImbruvica · 4.5 · Strong CYP3A4 inhibitors Co-administration of ketoconazole, a very strong CYP3A4 inhibitor, in 18 fasted healt
Eintrag öffnenImbruvica · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenImbruvica · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenImbruvica · 4.8 Undesirable effects · 1
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