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Intuniv · 4.5 · In an interaction study, neither guanfacine nor Osmotic Release Oral System (OROS)-methylphenidate HCl extende
Eintrag öffnenIntuniv · 4.5 · Interaction studies have only been performed in adults. However, the outcome is expected to be similar in the
Eintrag öffnenIntuniv · 4.5 · Lisdexamfetamine dimesylate
Eintrag öffnenIntuniv · 4.5 · Moderate CYP3A4/5 Strong CYP3A4/5 inhibitors CYP3A4 inducers inhibitors Aprepitant Boceprevir Bosentan Atazana
Eintrag öffnenIntuniv · 4.5 · Oral methylphenidate
Eintrag öffnenIntuniv · 4.5 · QT prolonging medicinal products
Eintrag öffnenIntuniv · 4.5 · The pharmacodynamic effect of guanfacine can have an additive effect when taken with other products known to c
Eintrag öffnenIntuniv · 4.5 · Valproic acid
Eintrag öffnenIntuniv · 4.5 · When guanfacine is used concomitantly with CYP3A4/5 inhibitors or inducers, plasma concentrations of guanfacin
Eintrag öffnenIntuniv · 4.5 · When patients are taking guanfacine concomitantly with a CYP3A4 inducer, an increase in the dose of guanfacine
Eintrag öffnenIntuniv · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenIntuniv · 4.8 Undesirable effects · 1
Eintrag öffnenIntuniv · 4.8 · 10 Table 4. Adverse reactions
Eintrag öffnenIntuniv · 4.8 · 11 System/Organ Class Incidence Category Adverse reaction Dry mouth Common Dyspepsia Uncommon
Eintrag öffnenIntuniv · 4.8 · 12 cross-over study in healthy adults. An apparent increase in mean QTc was observed for both doses. This find
Eintrag öffnenIntuniv · 4.8 · Adult patients
Eintrag öffnenIntuniv · 4.8 · Blood pressure and heart rate increase upon discontinuation of guanfacine
Eintrag öffnenIntuniv · 4.8 · Blood pressure and pulse may increase following discontinuation of guanfacine. In post-marketing experience, h
Eintrag öffnenIntuniv · 4.8 · Cardiac disorders Bradycardia Common Atrioventricular block first degree Uncommon Tachycardia Uncommon Sinus a
Eintrag öffnenIntuniv · 4.8 · Careful follow-up for weight suggests that children and adolescents who took guanfacine in the study (i.e., tr
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