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Ituxredi · 4.8 · Additional reactions reported in some cases were myocardial infarction, atrial fibrillation, pulmonary oedema
Eintrag öffnenItuxredi · 4.8 · Adult induction of remission (GPA/MPA Study 1) In GPA/MPA Study 1, 99 adult patients were treated for inductio
Eintrag öffnenItuxredi · 4.8 · Adult maintenance treatment (GPA/MPA Study 2) In GPA/MPA Study 2, a total of 57 adult patients with severe, ac
Eintrag öffnenItuxredi · 4.8 · Adverse reactions are listed in Table 4. Frequencies are defined as very common (≥ 1/10), common (≥ 1/100 to <
Eintrag öffnenItuxredi · 4.8 · Bulky disease There was a higher incidence of grade 3/4 adverse reactions in patients with bulky disease than
Eintrag öffnenItuxredi · 4.8 · Cardiovascular adverse reactions Cardiovascular reactions during clinical trials with rituximab monotherapy we
Eintrag öffnenItuxredi · 4.8 · Cardiovascular adverse reactions In GPA/MPA Study 1, cardiac events occurred at a rate of approximately 273 pe
Eintrag öffnenItuxredi · 4.8 · Cardiovascular adverse reactions Serious cardiac reactions were reported at a rate of 1.3 per 100 patient year
Eintrag öffnenItuxredi · 4.8 · Cases of progressive multifocal leukoencephalopathy with fatal outcome have been reported following use of rit
Eintrag öffnenItuxredi · 4.8 · Description of selected adverse reactions
Eintrag öffnenItuxredi · 4.8 · During the overall study period, the safety profile of rituximab was consistent with that reported during the
Eintrag öffnenItuxredi · 4.8 · Experience from granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA)
Eintrag öffnenItuxredi · 4.8 · Experience from non-Hodgkin’s lymphoma and chronic lymphocytic leukaemia in adults
Eintrag öffnenItuxredi · 4.8 · Experience from paediatric DLBCL/BL/BAL/BLL
Eintrag öffnenItuxredi · 4.8 · Experience from pemphigus vulgaris
Eintrag öffnenItuxredi · 4.8 · Experience from rheumatoid arthritis
Eintrag öffnenItuxredi · 4.8 · Gastrointestinal disorders Gastrointestinal perforation in some cases leading to death has been observed in pa
Eintrag öffnenItuxredi · 4.8 · Haematologic adverse reactions In clinical trials with rituximab monotherapy given for 4 weeks, haematological
Eintrag öffnenItuxredi · 4.8 · Hepatitis-B reactivation A small number of cases of hepatitis-B reactivation, some with fatal outcome, have be
Eintrag öffnenItuxredi · 4.8 · Hypogammaglobulinaemia Hypogammaglobulinaemia (IgA, IgG or IgM below the lower limit of normal) has been obser
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