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Latuda · 4.5 · Lurasidone is an in vitro inhibitor of the efflux transporter BCRP and the clinical relevance of intestinal BC
Eintrag öffnenLatuda · 4.5 · Pharmacodynamic interactions Given the primary central nervous system effects of lurasidone, lurasidone should
Eintrag öffnenLatuda · 4.5 · Pharmacokinetic interactions The concomitant administration of lurasidone and grapefruit juice has not been as
Eintrag öffnenLatuda · 4.5 · Potential for other medicinal products to affect lurasidone Lurasidone and its active metabolite ID-14283 both
Eintrag öffnenLatuda · 4.5 · Transporters Lurasidone is a substrate of P-gp and BCRP in vitro and the in vivo relevance of this is unclear.
Eintrag öffnenLatuda · 4.5 · When lurasidone is coadministered with mild or moderate CYP3A4 inducers, the efficacy of lurasidone needs to b
Eintrag öffnenLatuda · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenLatuda · 4.8 Undesirable effects · 1
Eintrag öffnenLatuda · 4.8 · 10 System Organ Very Common Uncommon Rare Frequency Class Common not known Panic Attack Psychomotor hyperactiv
Eintrag öffnenLatuda · 4.8 · 11 System Organ Very Common Uncommon Rare Frequency Class Common not known Musculoskeletal Muscle rigidity Art
Eintrag öffnenLatuda · 4.8 · 12 System Organ Very Common Uncommon Rare Frequency Class Common not known Investigations Blood creatine Alani
Eintrag öffnenLatuda · 4.8 · 13 subjects versus 5.8% for placebo-treated subjects. The incidence of akathisia for lurasidone-treated subjec
Eintrag öffnenLatuda · 4.8 · 8 System Organ Very Common Uncommon Rare Frequency not Class Commo known n Vascular Hypertension Hypotension d
Eintrag öffnenLatuda · 4.8 · 9 System Organ Very Common Uncommon Rare Frequency not Class Commo known n Investigations Blood creatinine pho
Eintrag öffnenLatuda · 4.8 · Description of selected adverse reactions Post marketing reports of clinically serious cases of skin and other
Eintrag öffnenLatuda · 4.8 · Dystonia: Symptoms of dystonia, prolonged abnormal contractions of muscle groups, may occur in susceptible ind
Eintrag öffnenLatuda · 4.8 · Events of interest to the class Extrapyramidal symptoms (EPS): In the adult short-term placebo-controlled stud
Eintrag öffnenLatuda · 4.8 · General Fatigue Gait Sudden death disorders and disturbance administration site conditions
Eintrag öffnenLatuda · 4.8 · Metabolism Weight Blood glucose and nutrition increased increased disorders Decreased Hyponatraemia appetite
Eintrag öffnenLatuda · 4.8 · Nervous Akathisi Somnolence* Lethargy Neuroleptic system a Parkinsonism* Dysarthria malignant disorders * Tard
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