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Libtayo · 4.8 · Adverse events were serious in 25.3% of patients.
Eintrag öffnenLibtayo · 4.8 · Adverse events were serious in 32.4% of patients.
Eintrag öffnenLibtayo · 4.8 · Cemiplimab as monotherapy The safety of cemiplimab as monotherapy has been evaluated in 1281 patients with adv
Eintrag öffnenLibtayo · 4.8 · Cemiplimab in combination with platinum‐based chemotherapy
Eintrag öffnenLibtayo · 4.8 · Description of selected adverse reactions The selected adverse reactions described below are based on safety o
Eintrag öffnenLibtayo · 4.8 · Hyperthyroidism occurred in 39 (3.0%) of 1281 patients receiving cemiplimab, including 1 (< 0.1%) patient with
Eintrag öffnenLibtayo · 4.8 · Immune checkpoint inhibitor class effects
Eintrag öffnenLibtayo · 4.8 · Immune-mediated adverse reactions (see section 4.2 and section 4.4)
Eintrag öffnenLibtayo · 4.8 · Immune-mediated adverse reactions occurred in 18.9% of patients including Grade 5 (0.3%), Grade 3 (2.6%), and
Eintrag öffnenLibtayo · 4.8 · Immune-mediated adverse reactions occurred in 21% of patients treated with cemiplimab in clinical trials inclu
Eintrag öffnenLibtayo · 4.8 · Immune-mediated colitis Immune-mediated diarrhoea or colitis occurred in 25 (2.0%) of 1281 patients receiving
Eintrag öffnenLibtayo · 4.8 · Immune-mediated endocrinopathies Hypothyroidism occurred in 87 (6.8%) of 1281 patients receiving cemiplimab, i
Eintrag öffnenLibtayo · 4.8 · Immune-mediated hepatitis Immune-mediated hepatitis occurred in 31 (2.4%) of 1281 patients receiving cemiplima
Eintrag öffnenLibtayo · 4.8 · Immune-mediated hypophysitis occurred in 7 (0.5%) of 1281 patients receiving cemiplimab, including 3 (0.2%) pa
Eintrag öffnenLibtayo · 4.8 · Immune-mediated nephritis Immune-mediated nephritis occurred in 9 (0.7%) of 1281 patients receiving cemiplimab
Eintrag öffnenLibtayo · 4.8 · Immune-mediated pneumonitis Immune-mediated pneumonitis occurred in 33 (2.6%) of 1281 patients receiving cemip
Eintrag öffnenLibtayo · 4.8 · Immune-mediated skin adverse reactions Immune-mediated skin adverse reactions occurred in 24 (1.9%) of 1281 pa
Eintrag öffnenLibtayo · 4.8 · Immunogenicity As with all therapeutic proteins, there is a potential for immunogenicity with cemiplimab. In c
Eintrag öffnenLibtayo · 4.8 · Infusion-related reactions Infusion-related reactions occurred in 94 (7.3%) of 1281 patients treated with cemi
Eintrag öffnenLibtayo · 4.8 · Nervous system disorders: Aseptic meningitis, paraneoplastic encephalomyelitis (Grade 5), chronic inflammatory
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