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Darunavir Krka · 4.5 · Ritonavir inhibits the transporters P-glycoprotein, OATP1B1 and OATP1B3, and co-administration with substrates
Eintrag öffnenDarunavir Viatris (previously Darunavir Mylan) · 4.5 · 49 OATP1B1 and OATP1B3 (see contraindications and recommendations presented in the section above). Cobicistat
Eintrag öffnenDarunavir Viatris (previously Darunavir Mylan) · 4.5 · Ritonavir inhibits the transporters P-glycoprotein, OATP1B1 and OATP1B3, and co-administration with substrates
Eintrag öffnenDarunavir Viatris (previously Darunavir Mylan) · 4.5 · Ritonavir inhibits the transporters P-glycoprotein, OATP1B1 and OATP1B3, and co-administration with substrates
Eintrag öffnenEntresto · 4.5 · OATP and MRP2 transporters The active metabolite of sacubitril (LBQ657) and valsartan are OATP1B1, OATP1B3, OA
Eintrag öffnenEntresto · 4.5 · OATP and MRP2 transporters The active metabolite of sacubitril (LBQ657) and valsartan are OATP1B1, OATP1B3, OA
Eintrag öffnenEntresto · 4.5 · OATP1B1 and OATP1B3 substrates, e.g. statins In vitro data indicate that sacubitril inhibits OATP1B1 and OATP1
Eintrag öffnenEntresto · 4.5 · OATP1B1 and OATP1B3 substrates, e.g. statins In vitro data indicate that sacubitril inhibits OATP1B1 and OATP1
Eintrag öffnenErivedge · 4.5 · In vitro, vismodegib is an inhibitor of OATP1B1. It cannot be excluded that vismodegib may increase the exposu
Eintrag öffnenEtcamah · 4.5 · OATP1B1 sensitive substrates In vitro data show that camizestrant is an inhibitor of OATP1B1. Therefore, camiz
Eintrag öffnenEvrenzo · 4.5 · OATP1B1 or BCRP substrates Roxadustat is an inhibitor of BCRP and OATP1B1. These transporters play an importan
Eintrag öffnenEvrenzo · 4.5 · Roxadustat may increase the plasma exposure of other medicinal products that are substrates of BCRP or OATP1B1
Eintrag öffnenFabhalta · 4.5 · Strong inducers of CYP2C8, UGT1A1, PgP, BCRP and OATP1B1/3 Although concomitant administration of iptacopan wi
Eintrag öffnenFilspari · 4.5 · Co-administration of 800 mg sparsentan decreased pitavastatin (a substrate of OATP1B1 and OATP1B3) Cmax by 19%
Eintrag öffnenFinlee · 4.5 · Dabrafenib is an in vitro inhibitor of human organic anion transporting polypeptide (OATP) 1B1 (OATP1B1), OATP
Eintrag öffnenGlyxambi · 4.5 · An interaction study with gemfibrozil, an in vitro inhibitor of OAT3 and OATP1B1/1B3 transporters, showed that
Eintrag öffnenGlyxambi · 4.5 · Inhibition of OATP1B1/1B3 transporters by co-administration with rifampicin resulted in a 75% increase in Cmax
Eintrag öffnenHalaven · 4.5 · At relevant clinical concentrations, eribulin did not inhibit BCRP, OCT1, OCT2, OAT1, OAT3, OATP1B1 and OATP1B
Eintrag öffnenHepcludex · 4.5 · In vitro an inhibition of OATP1B1/3 transporters by bulevirtide was observed, albeit only at a concentration ≥
Eintrag öffnenIfirmacombi · 4.5 · Repaglinide: Irbesartan has the potential to inhibit OATP1B1. In a clinical study, it was reported that irbesa
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