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Begriffe & Kennungen
Ocrevus · 4.5 · No interaction studies have been performed, as no interactions are expected via cytochrome P450 enzymes, other
Eintrag öffnenOcrevus · 4.5 · The safety of immunisation with live or live-attenuated vaccines, following ocrelizumab therapy has not been s
Eintrag öffnenOcrevus · 4.5 · The safety of immunisation with live or live-attenuated vaccines, following ocrelizumab therapy has not been s
Eintrag öffnenOcrevus · 4.5 · Vaccinations
Eintrag öffnenOcrevus · 4.5 · Vaccinations
Eintrag öffnenOcrevus · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenOcrevus · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenOcrevus · 4.8 Undesirable effects · 1
Eintrag öffnenOcrevus · 4.8 Undesirable effects · 2
Eintrag öffnenOcrevus · 4.8 · 13 Table 4 Adverse reactions
Eintrag öffnenOcrevus · 4.8 · 14 In the pivotal placebo-controlled (PPMS) clinical trial, IRR was the most common adverse reaction in the oc
Eintrag öffnenOcrevus · 4.8 · 15 In the pivotal PPMS clinical trial, 48.8% of ocrelizumab treated patients and 42.7% of patients who receive
Eintrag öffnenOcrevus · 4.8 · 16 Lymphocytes
Eintrag öffnenOcrevus · 4.8 · 17 majority of IRRs were mild to moderate. One IRR was reported as serious (with a Grade 3 intensity at Dose 1
Eintrag öffnenOcrevus · 4.8 · 40 Table 1 Adverse reactions
Eintrag öffnenOcrevus · 4.8 · 41 In OCARINA I, 125 patients received one or more subcutaneous injections of ocrelizumab 1200 mg. Of the 125
Eintrag öffnenOcrevus · 4.8 · 42 COVID-19 and COVID-19 pneumonia
Eintrag öffnenOcrevus · 4.8 · 43 The majority of these decreases reported in intravenous ocrelizumab treated patients were Grade 1 (<LLN – 8
Eintrag öffnenOcrevus · 4.8 · Across the RMS and PPMS trials, symptoms associated with IRRs included, but are not limited to: pruritus, rash
Eintrag öffnenOcrevus · 4.8 · Adverse reactions reported in clinical trials and derived from spontaneous reporting are listed below in Table
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