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Orladeyo · 4.5 · CYP2D6 substrates Berotralstat is a moderate inhibitor of CYP2D6, increasing the Cmax and AUC of dextromethorp
Eintrag öffnenOrladeyo · 4.5 · CYP3A4 substrates Berotralstat is a moderate inhibitor of CYP3A4, increasing the Cmax and AUC of oral midazola
Eintrag öffnenOrladeyo · 4.5 · CYP3A4 substrates Berotralstat is a moderate inhibitor of CYP3A4, increasing the Cmax and AUC of oral midazola
Eintrag öffnenOrladeyo · 4.5 · Effects of berotralstat on other medicinal products
Eintrag öffnenOrladeyo · 4.5 · Effects of berotralstat on other medicinal products
Eintrag öffnenOrladeyo · 4.5 · Effects of other medicinal products on berotralstat
Eintrag öffnenOrladeyo · 4.5 · Effects of other medicinal products on berotralstat
Eintrag öffnenOrladeyo · 4.5 · P-gp and BCRP inducers Berotralstat is a substrate of P-gp and BCRP. P-gp and BCRP inducers (e.g. rifampicin,
Eintrag öffnenOrladeyo · 4.5 · P-gp and BCRP inducers Berotralstat is a substrate of P-gp and BCRP. P-gp and BCRP inducers (e.g. rifampicin,
Eintrag öffnenOrladeyo · 4.5 · P-gp and BCRP inhibitors Ciclosporine, a P-gp and BCRP inhibitor, decreased the maximum concentration (Cmax) o
Eintrag öffnenOrladeyo · 4.5 · P-gp and BCRP inhibitors Ciclosporine, a P-gp and BCRP inhibitor, decreased the maximum concentration (Cmax) o
Eintrag öffnenOrladeyo · 4.5 · P-gp substrates Berotralstat is a weak inhibitor of P-gp and increased the Cmax and AUC of the P-gp substrate
Eintrag öffnenOrladeyo · 4.5 · P-gp substrates Berotralstat is a weak inhibitor of P-gp and increased the Cmax and AUC of the P-gp substrate
Eintrag öffnenOrladeyo · 4.5 · The effect of berotralstat on the CYP2C9 conversion of desogestrel to etonogestrel (active metabolite) was neg
Eintrag öffnenOrladeyo · 4.5 · The effect of berotralstat on the CYP2C9 conversion of desogestrel to etonogestrel (active metabolite) was neg
Eintrag öffnenOrladeyo · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenOrladeyo · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenOrladeyo · 4.8 Undesirable effects · 1
Eintrag öffnenOrladeyo · 4.8 Undesirable effects · 2
Eintrag öffnenOrladeyo · 4.8 · 19 29 paediatric patients aged 3 to < 12 years. Adverse reactions obtained from clinical studies and post- mar
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