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Ozawade · 4.5 · Medicinal products affecting pitolisant metabolism - CYP2D6 inhibitors CYP2D6 inhibitors will most likely have
Eintrag öffnenOzawade · 4.5 · Medicinal products that pitolisant may affect metabolism - CYP3A4 and CYP2B6 substrates A clinical induction s
Eintrag öffnenOzawade · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenOzawade · 4.5 · Pharmacodynamic interactions
Eintrag öffnenOzawade · 4.5 · Pharmacokinetic interactions
Eintrag öffnenOzawade · 4.5 · Pitolisant decreases the olanzapine exposure by 0.3-fold.
Eintrag öffnenOzawade · 4.5 · QT-prolonging substances or known to increase the risk of repolarization disorders (e.g. haloperidol, risperid
Eintrag öffnenOzawade · 4.5 · Tri or tetracyclic antidepressants with anti-histaminic H1-receptor properties (e.g. imipramine, clomipramine,
Eintrag öffnenOzawade · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenOzawade · 4.8 Undesirable effects · 1
Eintrag öffnenOzawade · 4.8 · 7 Hypoglycaemia Weight decreased Weight increased Psychiatric disorders Insomnia (all types) Confusional arous
Eintrag öffnenOzawade · 4.8 · 8 Musculoskeletal and Limb discomfort connective tissue disorders Muscle spasms Myalgia Arthralgia Tendonitis
Eintrag öffnenOzawade · 4.8 · Common Uncommon Infections and infestations Herpes zoster Viral upper respiratory tract infection Blood and ly
Eintrag öffnenOzawade · 4.8 · Description of selected adverse reactions
Eintrag öffnenOzawade · 4.8 · Gastric disorders Gastric disorders presumably caused by hyperacidity have been reported during clinical studi
Eintrag öffnenOzawade · 4.8 · Headache and insomnia During clinical studies in OSA indication, episodes of headache and insomnia have been r
Eintrag öffnenOzawade · 4.8 · Patients with low/normal Body Mass Index (BMI) (<25) Headache, insomnia, nausea and anxiety have been reported
Eintrag öffnenOzawade · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenOzawade · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenOzawade · 4.8 · Summary of the safety profile
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