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Qaialdo · 4.5 · Spironolactone binds to the androgen receptor and may increase prostate specific antigen (PSA) levels in abira
Eintrag öffnenQaialdo · 4.5 · Spironolactone enhances the metabolism of antipyrine.
Eintrag öffnenQaialdo · 4.5 · Spironolactone has been shown to increase the half-life of digoxin. Spironolactone has been reported to increa
Eintrag öffnenQaialdo · 4.5 · Spironolactone may reduce mitotane plasma levels in adrenocortical carcinoma patients treated with mitotane an
Eintrag öffnenQaialdo · 4.5 · Spironolactone reduces the renal clearance of lithium, thus increasing the risk of lithium toxicity. Monitor l
Eintrag öffnenQaialdo · 4.5 · Spironolactone reduces vascular responsiveness to noradrenaline.
Eintrag öffnenQaialdo · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenQaialdo · 4.8 Undesirable effects · 1
Eintrag öffnenQaialdo · 4.8 · 8 Table 2 Tabulated list of adverse reactions
Eintrag öffnenQaialdo · 4.8 · 9 Paediatric population
Eintrag öffnenQaialdo · 4.8 · Frequency, type and severity of adverse reactions in children are expected to be similar to adults.
Eintrag öffnenQaialdo · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenQaialdo · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenQaialdo · 4.8 · Summary of the safety profile
Eintrag öffnenQaialdo · 4.8 · System organ class Frequency Adverse reactions Neoplasms benign, malignant Uncommon Benign breast neoplasm (ma
Eintrag öffnenQaialdo · 4.8 · The following undesirable effects have been observed in clinical trials and reported during treatment with spi
Eintrag öffnenQaialdo · 4.8 · The most frequent adverse reactions of spironolactone include: hyperkalaemia, reported in 17.5% of patients, p
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