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Quviviq · 4.5 · Interaction studies have only been performed in adults.
Eintrag öffnenQuviviq · 4.5 · No clinical study was conducted with a strong CYP3A4 inhibitor. Concomitant use of QUVIVIQ with strong inhibit
Eintrag öffnenQuviviq · 4.5 · Pharmacodynamic interactions
Eintrag öffnenQuviviq · 4.5 · Substrates of BCRP or P-gp transporters In clinical studies conducted in healthy subjects receiving 25 mg and
Eintrag öffnenQuviviq · 4.5 · Substrates of CYP2C9 In a clinical study conducted in healthy subjects receiving daridorexant and warfarin, a
Eintrag öffnenQuviviq · 4.5 · Substrates of CYP3A4 In a clinical study conducted in healthy subjects receiving daridorexant and midazolam, a
Eintrag öffnenQuviviq · 4.5 · The consumption of grapefruit or grapefruit juice in the evening should be avoided.
Eintrag öffnenQuviviq · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenQuviviq · 4.8 Undesirable effects · 1
Eintrag öffnenQuviviq · 4.8 · 7 The majority of adverse reactions were mild to moderate in intensity. No evidence of a dose- relationship fo
Eintrag öffnenQuviviq · 4.8 · Description of selected adverse reactions
Eintrag öffnenQuviviq · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenQuviviq · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenQuviviq · 4.8 · Sleep paralysis and hallucinations Sleep paralysis was reported in 0.5% and 0.3% subjects receiving daridorexa
Eintrag öffnenQuviviq · 4.8 · Somnolence Somnolence was reported in 3% and 2% of subjects treated with daridorexant 25 mg and 50 mg, respect
Eintrag öffnenQuviviq · 4.8 · Summary of safety profile
Eintrag öffnenQuviviq · 4.8 · System organ class Adverse reaction Frequency Immune system disorders Hypersensitivity (including Uncommon ras
Eintrag öffnenQuviviq · 4.8 · Table 1 shows adverse reactions that occurred in Study 1 and Study 2 or in post-marketing experience.
Eintrag öffnenQuviviq · 4.8 · Table 1: Adverse reactions
Eintrag öffnenQuviviq · 4.8 · Tabulated list of adverse reactions
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