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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Rasilez“
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Rasilez · 4.5 · Dual blockade of the RAAS with aliskiren, ARBs or ACEIs Clinical trial data has shown that dual blockade of th
Eintrag öffnenRasilez · 4.5 · Food interactions Although meals (low or high fat content) have been shown to reduce the absorption of aliskir
Eintrag öffnenRasilez · 4.5 · Fruit juice and drinks containing plant extracts Administration of fruit juice with aliskiren resulted in a de
Eintrag öffnenRasilez · 4.5 · Furosemide and torasemide Oral co-administration of aliskiren and furosemide had no effect on the pharmacokine
Eintrag öffnenRasilez · 4.5 · In patients treated with both aliskiren and oral furosemide or torasemide, it is therefore recommended that th
Eintrag öffnenRasilez · 4.5 · Medicinal products affecting serum potassium levels Concomitant use of other agents affecting the RAAS, of NSA
Eintrag öffnenRasilez · 4.5 · Moderate P-gp inhibitors Co-administration of ketoconazole (200 mg) or verapamil (240 mg) with aliskiren (300
Eintrag öffnenRasilez · 4.5 · Non-steroidal anti-inflammatory drugs (NSAIDs) NSAIDs may reduce the anti-hypertensive effect of aliskiren. In
Eintrag öffnenRasilez · 4.5 · Not recommended
Eintrag öffnenRasilez · 4.5 · Organic anion transporting polypeptide (OATP) inhibitors Preclinical studies indicate that aliskiren might be
Eintrag öffnenRasilez · 4.5 · P-gp interactions MDR1/Mdr1a/1b (P-gp) was found to be the major efflux system involved in intestinal absorpti
Eintrag öffnenRasilez · 4.5 · P-gp potent inhibitors A single dose interaction study in healthy subjects has shown that ciclosporin (200 and
Eintrag öffnenRasilez · 4.5 · P-gp substrates or weak inhibitors No relevant interactions with atenolol, digoxin, amlodipine or cimetidine h
Eintrag öffnenRasilez · 4.5 · Pharmacokinetic interaction with other medicinal products Compounds that have been investigated in clinical ph
Eintrag öffnenRasilez · 4.5 · Warfarin The effects of aliskiren on warfarin pharmacokinetics have not been evaluated.
Eintrag öffnenRasilez · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenRasilez · 4.8 Undesirable effects · 1
Eintrag öffnenRasilez · 4.8 · 8 Table 1
Eintrag öffnenRasilez · 4.8 · Aliskiren has been evaluated for safety in a randomised, double-blind, 8-week study in 267 hypertensive patien
Eintrag öffnenRasilez · 4.8 · Aliskiren has been evaluated for safety in more than 7,800 patients, including over 2,300 treated for over 6 m
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