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Riximyo · 4.8 · 19 received rituximab in combination with chemotherapy or as part of a haematopoietic stem cell transplant. Ex
Eintrag öffnenRiximyo · 4.8 · 20 failure, myocardial disease and manifestations of coronary artery disease. In CLL, the overall incidence of
Eintrag öffnenRiximyo · 4.8 · 21 Re-treatment The percentage of patients reporting adverse reactions upon re-treatment with further courses
Eintrag öffnenRiximyo · 4.8 · 22 The adverse reactions identified only during post marketing surveillance, and for which a frequency could n
Eintrag öffnenRiximyo · 4.8 · 23 MedDRA Not known System organ Very common Common Uncommon Rare Very rare class Cardiac Angina Atrial disord
Eintrag öffnenRiximyo · 4.8 · 24 exposure to rituximab. The incidence of IRRs declined with subsequent infusions. In clinical trials fewer t
Eintrag öffnenRiximyo · 4.8 · 25 Neutropenic events, including severe late onset and persistent neutropenia, have been rarely reported in th
Eintrag öffnenRiximyo · 4.8 · 26 MedDRA Not known Very common Common System organ class Respiratory, thoracic cough, nasal congestion and me
Eintrag öffnenRiximyo · 4.8 · 27 Long-term follow-up (GPA/MPA Study 3) In a long-term observational safety study, 97 GPA and MPA patients re
Eintrag öffnenRiximyo · 4.8 · 28 The rate of serious infections was approximately 25 per 100 patient years. The most frequently reported ser
Eintrag öffnenRiximyo · 4.8 · 29 25%, 50% and 46% in the cyclophosphamide group. The rate of overall infections and serious infections was n
Eintrag öffnenRiximyo · 4.8 · 30 The adverse reactions identified only during post-marketing surveillance, and for which a frequency could n
Eintrag öffnenRiximyo · 4.8 · 31 In PV Study 2, IRRs occurred primarily at the first infusion and the frequency of IRRs decreased with subse
Eintrag öffnenRiximyo · 4.8 · A multicentre, open-label randomised study of Lymphome Malin B chemotherapy (LMB) with or without rituximab wa
Eintrag öffnenRiximyo · 4.8 · A small number of spontaneous and literature cases of hypogammaglobulinaemia have been observed in paediatric
Eintrag öffnenRiximyo · 4.8 · A small number of spontaneous and literature cases of hypogammaglobulinaemia have been observed in paediatric
Eintrag öffnenRiximyo · 4.8 · A total of 309 paediatric patients received rituximab and were included in the safety analysis population. Pae
Eintrag öffnenRiximyo · 4.8 · Additional reactions reported in some cases were myocardial infarction, atrial fibrillation, pulmonary oedema
Eintrag öffnenRiximyo · 4.8 · Adult induction of remission (GPA/MPA Study 1) In GPA/MPA Study 1, 99 adult patients were treated for inductio
Eintrag öffnenRiximyo · 4.8 · Adult maintenance treatment (GPA/MPA Study 2) In GPA/MPA Study 2, a total of 57 adult patients with severe, ac
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