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Sarclisa · 4.5 · Isatuximab may be detected on serum protein electrophoresis (SPE) and immunofixation (IFE) assays used for mon
Eintrag öffnenSarclisa · 4.5 · The pharmacokinetics of subcutaneous isatuximab, and concomitant pomalidomide, carfilzomib, bortezomib, and le
Eintrag öffnenSarclisa · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenSarclisa · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenSarclisa · 4.8 Undesirable effects · 1
Eintrag öffnenSarclisa · 4.8 Undesirable effects · 2
Eintrag öffnenSarclisa · 4.8 · 10 In IMROZ, the most frequent adverse reactions are diarrhoea (54.8%), peripheral sensory neuropathy (54.4%),
Eintrag öffnenSarclisa · 4.8 · 11 Anaemia Common 6.1 % 4.5 %
Eintrag öffnenSarclisa · 4.8 · 12 Thrombocytopenia Common 2.8 % 2.3 %
Eintrag öffnenSarclisa · 4.8 · 13 Incidence System organ Adverse reaction Frequency (N=336) class Any Grade Grade ≥3 Preferred term Lymphopen
Eintrag öffnenSarclisa · 4.8 · 14 Incidence System organ Adverse reaction Frequency (N=330) class Any Grade Grade ≥3 Preferred term Injury, p
Eintrag öffnenSarclisa · 4.8 · 15 2.7 % in the Pd group. Discontinuations from treatment due to infection were reported in 2.6 % of patients
Eintrag öffnenSarclisa · 4.8 · 16 Table 10: Haematology laboratory abnormalities in patients receiving isatuximab combined with carfilzomib a
Eintrag öffnenSarclisa · 4.8 · 17 patients less than 65, 14.4% of patients 65-74, and 15.9% of patients 75 or older. In the IMROZ study, no G
Eintrag öffnenSarclisa · 4.8 · 45 reactions with a lower incidence reported with isatuximab subcutaneous (3.1%) versus isatuximab intravenous
Eintrag öffnenSarclisa · 4.8 · 46 System organ Incidence class (N = 827) Adverse reaction Frequency Any Grade Grade ≥3 Preferred term
Eintrag öffnenSarclisa · 4.8 · 47 Isatuximab in combination with carfilzomib and dexamethasone (Isa-Kd)
Eintrag öffnenSarclisa · 4.8 · 48 System organ Adverse reaction Frequency Incidence class (N = 251) Preferred term Any Grade ≥3 Grade Respira
Eintrag öffnenSarclisa · 4.8 · 49 with isatuximab intravenous 10 mg/kg (763 patients). Data include patients from IsaSoCut (IIT17756), GMMG-H
Eintrag öffnenSarclisa · 4.8 · 50 System organ Adverse reaction Frequency Incidence class (N = 904) Preferred term Any Grade ≥3 Grade disorde
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