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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Sprycel“
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Sprycel · 4.5 · Antacids Non-clinical data demonstrate that the solubility of dasatinib is pH-dependent. In healthy subjects,
Eintrag öffnenSprycel · 4.5 · At clinically relevant concentrations, binding of dasatinib to plasma proteins is approximately 96% on the bas
Eintrag öffnenSprycel · 4.5 · At clinically relevant concentrations, binding of dasatinib to plasma proteins is approximately 96% on the bas
Eintrag öffnenSprycel · 4.5 · Histamine-2 antagonists and proton pump inhibitors Long-term suppression of gastric acid secretion by H2 antag
Eintrag öffnenSprycel · 4.5 · Histamine-2 antagonists and proton pump inhibitors Long-term suppression of gastric acid secretion by H2 antag
Eintrag öffnenSprycel · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenSprycel · 4.5 · Paediatric population Interaction studies have only been performed in adults.
Eintrag öffnenSprycel · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenSprycel · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenSprycel · 4.8 Undesirable effects · 1
Eintrag öffnenSprycel · 4.8 Undesirable effects · 2
Eintrag öffnenSprycel · 4.8 · 13 Rare diabetes mellitus Psychiatric disorders Common depression, insomnia Uncommon anxiety, confusional stat
Eintrag öffnenSprycel · 4.8 · 14 Skin and subcutaneous tissue disorders Very common skin rashe Common alopecia, dermatitis (including eczema
Eintrag öffnenSprycel · 4.8 · 15 Description of selected adverse reactions Myelosuppression Treatment with SPRYCEL is associated with anaemi
Eintrag öffnenSprycel · 4.8 · 16 section 4.4). No additional patients were reported to have QTcF > 500 msec after a minimum of 60 months fol
Eintrag öffnenSprycel · 4.8 · 17 Table 6b: Selected adverse reactions reported in phase III dose-optimisation study: Advanced phase CML and
Eintrag öffnenSprycel · 4.8 · 18 Laboratory test abnormalities Haematology In the Phase III newly diagnosed chronic phase CML study, the fol
Eintrag öffnenSprycel · 4.8 · 2 year follow-up Grade 3 or 4 elevations of transaminases or bilirubin were reported in 1% of patients with ch
Eintrag öffnenSprycel · 4.8 · 2 year follow-up Grade 3 or 4 elevations of transaminases or bilirubin were reported in 1% of patients with ch
Eintrag öffnenSprycel · 4.8 · 49 Rare diabetes mellitus Psychiatric disorders Common depression, insomnia Uncommon anxiety, confusional stat
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