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Verzenios · 4.8 · Creatinine Although not an adverse reaction, abemaciclib has been shown to increase serum creatinine. In the m
Eintrag öffnenVerzenios · 4.8 · Description of selected adverse reactions
Eintrag öffnenVerzenios · 4.8 · Diarrhoea Diarrhoea was the most commonly reported adverse reaction (see Table 8). Incidence was greatest duri
Eintrag öffnenVerzenios · 4.8 · Gastrointestinal Diarrhoea Dyspepsia f disorders Vomiting Nausea Stomatitis f Skin and subcutaneous Alopecia g
Eintrag öffnenVerzenios · 4.8 · In the following table, adverse reactions are listed in order of MedDRA body system organ class and frequency.
Eintrag öffnenVerzenios · 4.8 · Increased aminotransferases In the monarchE study, ALT and AST elevations were reported frequently (12.3 % and
Eintrag öffnenVerzenios · 4.8 · Neutropenia Neutropenia was reported frequently across studies. In the monarchE study, neutropenia was reporte
Eintrag öffnenVerzenios · 4.8 · Of the most common adverse reactions, Grade ≥ 3 events were less than 5 % with the exception of neutropenia, l
Eintrag öffnenVerzenios · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenVerzenios · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenVerzenios · 4.8 · Respiratory, thoracic ILD/pneumonitis d and mediastinal disorders
Eintrag öffnenVerzenios · 4.8 · Summary of the safety profile
Eintrag öffnenVerzenios · 4.8 · System organ class Very common Common Uncommon Rare Infections and Infections b infestations Blood and lymphat
Eintrag öffnenVerzenios · 4.8 · Table 8. Adverse reactions reported in the phase 3 studies of abemaciclib in combination with endocrine therap
Eintrag öffnenVerzenios · 4.8 · Tabulated list of adverse reactions
Eintrag öffnenVerzenios · 4.8 · The most commonly occurring adverse reactions are diarrhoea, infections, neutropenia, leukopenia, anaemia, fat
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