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Voriconazole Hikma (previously Voriconazole Hospira) · 4.5 · 17 Finerenone Although not studied, voriconazole Contraindicated (see section [CYP3A4 substrate] is likely to
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · 18 Steroids Corticosteroids
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · 300 mg QD (coadministered Phenytoin Cmax ↑ 67% Phenytoin may be with voriconazole 400 mg Phenytoin AUCτ ↑ 81%
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Although not studied, voriconazole Contraindicated (see section Voclosporin is likely to significantly increas
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Azithromycin (500 mg QD) Voriconazole Cmax and AUCτ ↔
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Ciclosporin (in stable renal Ciclosporin Cmax ↑ 13% When initiating voriconazole in transplant recipients rece
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Compared to efavirenz 600 mg Voriconazole may be QD, coadministered with efavirenz if Efavirenz 300 mg QD, Efa
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Efavirenz 400 mg QD, Efavirenz Cmax ↑ 38% Use of standard doses of coadministered with Efavirenz AUCτ ↑ 44% vo
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Erythromycin (1 g BID) Voriconazole Cmax and AUCτ ↔ [CYP3A4 inhibitor] The effect of voriconazole on either er
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Everolimus Although not studied, voriconazole Coadministration of voriconazole [also P-gp substrate] is likely
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · High dose (400 mg BID) Ritonavir Cmax and AUCτ ↔ Coadministration of voriconazole Voriconazole Cmax ↓ 66% and
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Interaction table
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Interactions between voriconazole and other medicinal products are listed in the table below (once daily as “Q
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Low dose (100 mg BID)* Ritonavir Cmax ↓ 25% Coadministration of voriconazole Ritonavir AUCτ ↓13% and low-dose
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Medicinal product Interaction Recommendations concerning geometric mean changes (%) coadministration Antacids
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Midazolam (7.5 mg oral single In an independent published study, dose) Midazolam Cmax ↑ 3.8-fold Midazolam AUC
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Other benzodiazepines Although not studied, voriconazole (including but not limited to: is likely to increase
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Prednisolone (60 mg single Prednisolone Cmax ↑ 11% No dose adjustment dose) Prednisolone AUC0-∞ ↑ 34% [CYP3A4
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Sirolimus (2 mg single dose) In an independent published study, Coadministration of voriconazole Sirolimus Cma
Eintrag öffnenVoriconazole Hikma (previously Voriconazole Hospira) · 4.5 · Tacrolimus (0.1 mg/kg single Tacrolimus Cmax ↑ 117% When initiating voriconazole in dose) Tacrolimus AUCt ↑ 22
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