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Votubia · 4.5 · Agents whose plasma concentration may be altered by everolimus
Eintrag öffnenVotubia · 4.5 · Agents whose plasma concentration may be altered by everolimus
Eintrag öffnenVotubia · 4.5 · Based on in vitro results, the systemic concentrations obtained after oral daily doses of 10 mg make inhibitio
Eintrag öffnenVotubia · 4.5 · Based on in vitro results, the systemic concentrations obtained after oral daily doses of 10 mg make inhibitio
Eintrag öffnenVotubia · 4.5 · CYP3A4 and PgP inducers decreasing everolimus concentrations
Eintrag öffnenVotubia · 4.5 · CYP3A4 and PgP inhibitors increasing everolimus concentrations
Eintrag öffnenVotubia · 4.5 · CYP3A4 and PgP inhibitors increasing everolimus concentrations
Eintrag öffnenVotubia · 4.5 · Concomitant ketogenic diet
Eintrag öffnenVotubia · 4.5 · Concomitant use of ACE inhibitors
Eintrag öffnenVotubia · 4.5 · Discontinuation of one of multiple strong CYP3A4 inducers may not require additional dose adjustment. Assess t
Eintrag öffnenVotubia · 4.5 · Discontinuation of one of multiple strong CYP3A4 inducers may not require additional dose adjustment. Assess t
Eintrag öffnenVotubia · 4.5 · Everolimus is a substrate of CYP3A4, and also a substrate and moderate inhibitor of PgP. Therefore, absorption
Eintrag öffnenVotubia · 4.5 · Everolimus is a substrate of CYP3A4, and also a substrate and moderate inhibitor of PgP. Therefore, absorption
Eintrag öffnenVotubia · 4.5 · For patients not receiving concomitant strong inducers at the start of everolimus treatment, the co-administra
Eintrag öffnenVotubia · 4.5 · For patients with SEGA associated with TSC: If patients require co-administration of a moderate CYP3A4 or PgP
Eintrag öffnenVotubia · 4.5 · For patients with SEGA associated with TSC: Patients receiving concomitant potent CYP3A4 inducers may require
Eintrag öffnenVotubia · 4.5 · In EXIST-3 (Study CRAD001M2304), everolimus increased pre-dose concentrations of the antiepileptics carbamazep
Eintrag öffnenVotubia · 4.5 · In EXIST-3 (Study CRAD001M2304), everolimus increased pre-dose concentrations of the antiepileptics carbamazep
Eintrag öffnenVotubia · 4.5 · Known and theoretical interactions with selected inhibitors and inducers of CYP3A4 and PgP are listed in Table
Eintrag öffnenVotubia · 4.5 · Known and theoretical interactions with selected inhibitors and inducers of CYP3A4 and PgP are listed in Table
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