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Xtandi · 4.5 · CYP2C8 and CYP3A4 inducers Following oral administration of the moderate CYP2C8 and strong CYP3A4 inducer rifa
Eintrag öffnenXtandi · 4.5 · CYP2C8 inhibitors CYP2C8 plays an important role in the elimination of enzalutamide and in the formation of it
Eintrag öffnenXtandi · 4.5 · CYP2C8 inhibitors CYP2C8 plays an important role in the elimination of enzalutamide and in the formation of it
Eintrag öffnenXtandi · 4.5 · CYP3A4 inhibitors CYP3A4 plays a minor role in the metabolism of enzalutamide. Following oral administration o
Eintrag öffnenXtandi · 4.5 · CYP3A4 inhibitors CYP3A4 plays a minor role in the metabolism of enzalutamide. Following oral administration o
Eintrag öffnenXtandi · 4.5 · Effect of food on enzalutamide exposures Food has no clinically significant effect on the extent of exposure t
Eintrag öffnenXtandi · 4.5 · Effect of food on enzalutamide exposures Food has no clinically significant effect on the extent of exposure t
Eintrag öffnenXtandi · 4.5 · Enzyme induction Enzalutamide is a potent enzyme inducer and increases the synthesis of many enzymes and trans
Eintrag öffnenXtandi · 4.5 · Enzyme induction Enzalutamide is a potent enzyme inducer and increases the synthesis of many enzymes and trans
Eintrag öffnenXtandi · 4.5 · Groups of medicinal products that can be affected include, but are not limited to:
Eintrag öffnenXtandi · 4.5 · Groups of medicinal products that can be affected include, but are not limited to:
Eintrag öffnenXtandi · 4.5 · In vivo studies have shown that enzalutamide is a strong inducer of CYP3A4 and a moderate inducer of CYP2C9 an
Eintrag öffnenXtandi · 4.5 · In vivo studies have shown that enzalutamide is a strong inducer of CYP3A4 and a moderate inducer of CYP2C9 an
Eintrag öffnenXtandi · 4.5 · Interactions with certain medicinal products that are eliminated through metabolism or active transport are ex
Eintrag öffnenXtandi · 4.5 · Interactions with certain medicinal products that are eliminated through metabolism or active transport are ex
Eintrag öffnenXtandi · 4.5 · Laboratory Test Interference Falsely elevated digoxin plasma level results with the chemiluminescent micropart
Eintrag öffnenXtandi · 4.5 · Laboratory Test Interference Falsely elevated digoxin plasma level results with the chemiluminescent micropart
Eintrag öffnenXtandi · 4.5 · MRP2, OAT3 and OCT1 substrates Based on in vitro data, inhibition of MRP2 (in the intestine), as well as organ
Eintrag öffnenXtandi · 4.5 · MRP2, OAT3 and OCT1 substrates Based on in vitro data, inhibition of MRP2 (in the intestine), as well as organ
Eintrag öffnenXtandi · 4.5 · Medicinal products which prolong the QT interval Since androgen deprivation treatment may prolong the QT inter
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