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Xyrem · 4.5 · The co-administration of sodium oxybate (6 g per day) with valproate (1250 mg per day) resulted in an increase
Eintrag öffnenXyrem · 4.5 · The combined use of alcohol with sodium oxybate may result in potentiation of the central nervous system-depre
Eintrag öffnenXyrem · 4.5 · Topiramate Possible pharmacodynamic and pharmacokinetic interactions when sodium oxybate is used concomitantly
Eintrag öffnenXyrem · 4.5 · Tramadol A drug interaction study in healthy adults with sodium oxybate (single dose of 2.25 g) and tramadol (
Eintrag öffnenXyrem · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenXyrem · 4.8 Undesirable effects · 1
Eintrag öffnenXyrem · 4.8 · 10 headache (5.8%), dizziness (5.8%). Adverse drug reactions of suicidal ideation (1%) and of acute psychosis
Eintrag öffnenXyrem · 4.8 · 8 The safety profile was qualitatively the same in adult and paediatric studies.
Eintrag öffnenXyrem · 4.8 · 9 Ear and labyrinth disorders Common: vertigo Not known tinnitus
Eintrag öffnenXyrem · 4.8 · Cardiac disorders Common: palpitations
Eintrag öffnenXyrem · 4.8 · Clinical Studies
Eintrag öffnenXyrem · 4.8 · Description of selected adverse reactions In some patients, cataplexy may return at a higher frequency on cess
Eintrag öffnenXyrem · 4.8 · Eye disorders Common: blurred vision
Eintrag öffnenXyrem · 4.8 · Frequency estimate: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1000 to < 1/100); rare (≥
Eintrag öffnenXyrem · 4.8 · Gastrointestinal disorders Very common: nausea (the frequency of nausea is higher in women than men) Common: v
Eintrag öffnenXyrem · 4.8 · General disorders and administration site conditions Common: asthenia, fatigue, feeling drunk, oedema peripher
Eintrag öffnenXyrem · 4.8 · Immune system disorders Uncommon: hypersensitivity
Eintrag öffnenXyrem · 4.8 · In a study in children and adolescents the most frequently reported related TEAEs were enuresis (18.3%), nause
Eintrag öffnenXyrem · 4.8 · In adults the efficacy and safety of sodium oxybate for the treatment of narcolepsy symptoms was established i
Eintrag öffnenXyrem · 4.8 · In adults the most commonly reported adverse reactions were dizziness, nausea, and headache, all occurring in
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