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Yondelis · 4.8 · 9 System Organ Very Common Common Uncommon Rare Class Skin and Palmar-plantar Rash Subcutaneous erythrodysaest
Eintrag öffnenYondelis · 4.8 · Adverse reactions are listed by System Organ Class and frequency. The frequencies are classified as very commo
Eintrag öffnenYondelis · 4.8 · Anaemia: Anaemia occurred in 93% and 94% of patients treated with the monotherapy and combination regimens res
Eintrag öffnenYondelis · 4.8 · Blood and lymphatic system disorders
Eintrag öffnenYondelis · 4.8 · Capillary Leak Syndrome (CLS): Cases of Capillary Leak Syndrome (CLS) have been reported with trabectedin (inc
Eintrag öffnenYondelis · 4.8 · Description of selected adverse reactions
Eintrag öffnenYondelis · 4.8 · Fatal adverse reactions have occurred in 1.9% and 0.6% of patients treated with the monotherapy and combinatio
Eintrag öffnenYondelis · 4.8 · Hepatic failure: Rare cases of hepatic failure (including cases with fatal outcomes) have been reported in pat
Eintrag öffnenYondelis · 4.8 · Hepatobiliary disorders
Eintrag öffnenYondelis · 4.8 · Hyperbilirubinemia: Bilirubin peaks approximately a week after onset and resolves approximately two weeks afte
Eintrag öffnenYondelis · 4.8 · In the ET743-OVA-301 Yondelis+PLD arm, non-white (mainly Asian) patients had a higher incidence than white pat
Eintrag öffnenYondelis · 4.8 · Liver function tests predicting severe toxicity (meeting Hy´s law) and clinical manifestations of severe hepat
Eintrag öffnenYondelis · 4.8 · Most frequent adverse reactions
Eintrag öffnenYondelis · 4.8 · Most patients treated with Yondelis can be expected to have adverse reactions of any grade (91% in monotherapy
Eintrag öffnenYondelis · 4.8 · Neutropenia: Neutropenia is the most common haematological toxicity. It followed a predictable pattern of rapi
Eintrag öffnenYondelis · 4.8 · Other adverse reactions
Eintrag öffnenYondelis · 4.8 · Reporting of suspected adverse reactions
Eintrag öffnenYondelis · 4.8 · Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows con
Eintrag öffnenYondelis · 4.8 · Summary of the safety profile
Eintrag öffnenYondelis · 4.8 · System Organ Very Common Common Uncommon Rare Class Infections and Neutropenic infection Sepsis Septic shock I
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