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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „Yuvanci“
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Begriffe & Kennungen
Yuvanci · 4.5 · In clinical studies, tadalafil (5, 10 and 20 mg) was shown to augment the hypotensive effects of nitrates. Thi
Eintrag öffnenYuvanci · 4.5 · In patients receiving concomitant antihypertensive medicinal products, tadalafil 20 mg may induce a blood pres
Eintrag öffnenYuvanci · 4.5 · Ketoconazole (200 mg daily), increased tadalafil (10 mg) single dose exposure (AUC) 2-fold and Cmax by 15%, re
Eintrag öffnenYuvanci · 4.5 · Ketoconazole (400 mg daily) increased tadalafil (20 mg) single dose exposure (AUC) 4-fold and Cmax by 22%.
Eintrag öffnenYuvanci · 4.5 · Ketoconazole (400 mg once daily) increased exposure to macitentan approximately 2-fold. Exposure to the active
Eintrag öffnenYuvanci · 4.5 · Oral contraceptive pill In in vivo studies, macitentan 10 mg once daily did not affect the pharmacokinetics of
Eintrag öffnenYuvanci · 4.5 · P-glycoprotein substrates (e.g., digoxin) Tadalafil (40 mg once per day) had no clinically significant effect
Eintrag öffnenYuvanci · 4.5 · Pharmacodynamic interactions
Eintrag öffnenYuvanci · 4.5 · Pharmacokinetic interactions
Eintrag öffnenYuvanci · 4.5 · Prostacyclin and its analogues such as epoprostenol or iloprost
Eintrag öffnenYuvanci · 4.5 · Rifampicin (600 mg daily) reduced the steady-state exposure to macitentan by 79% but did not affect the exposu
Eintrag öffnenYuvanci · 4.5 · Rifampicin (600 mg daily), reduced tadalafil AUC by 88% and Cmax by 46%, relative to the AUC and Cmax values f
Eintrag öffnenYuvanci · 4.5 · Riociguat
Eintrag öffnenYuvanci · 4.5 · Ritonavir (200 mg twice daily), which is an inhibitor of CYP3A4, CYP2C9, CYP2C19, and CYP2D6, increased tadala
Eintrag öffnenYuvanci · 4.5 · Ritonavir (500 mg or 600 mg twice daily) increased tadalafil (20 mg) single-dose exposure (AUC) by 32% and dec
Eintrag öffnenYuvanci · 4.5 · Strong CYP3A4 inducers Potent inducers of CYP3A4 including rifampicin, St. John’s wort, carbamazepine, and phe
Eintrag öffnenYuvanci · 4.5 · Strong CYP3A4 inhibitors The combination of Yuvanci with strong CYP3A4 inhibitors such as itraconazole, ketoco
Eintrag öffnenYuvanci · 4.5 · Terbutaline A similar increase in AUC and Cmax seen with ethinylestradiol may be expected with oral administra
Eintrag öffnenYuvanci · 4.5 · The co-administration of doxazosin (4 and 8 mg daily) and tadalafil (5 mg daily dose and 20 mg as a single dos
Eintrag öffnenYuvanci · 4.5 · The efficacy and safety of Yuvanci co-administered with prostacyclin or its analogues has not been studied in
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