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Zeposia · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenZeposia · 4.8 Undesirable effects · 1
Eintrag öffnenZeposia · 4.8 · ** for patients with pre-existing factors (see section 4.4) *** including pulmonary function test decreased, s
Eintrag öffnenZeposia · 4.8 · 10 Frequencies are defined as: very common (≥ 1/10); common (≥ 1/100 to < 1/10); uncommon (≥ 1/1 000 to < 1/10
Eintrag öffnenZeposia · 4.8 · 11 treatment with ozanimod with values returning to less than 3-fold the ULN within approximately 2 to 4 weeks
Eintrag öffnenZeposia · 4.8 · 12 Infections In MS clinical studies, the overall rate of infections (35%) with ozanimod 0.92 mg was similar t
Eintrag öffnenZeposia · 4.8 · Blood lymphocyte count reduction In MS clinical studies, 3.3% of patients and in UC controlled clinical studie
Eintrag öffnenZeposia · 4.8 · Bradyarrhythmia After the initial dose of ozanimod 0.23 mg, the greatest mean reduction from baseline in sitti
Eintrag öffnenZeposia · 4.8 · Description of selected adverse reactions
Eintrag öffnenZeposia · 4.8 · Elevated hepatic enzymes In MS clinical studies, elevations of ALT to 5-fold the upper limit of normal (ULN) o
Eintrag öffnenZeposia · 4.8 · Herpetic infections In MS clinical studies, herpes zoster was reported as an adverse reaction in 0.6% of patie
Eintrag öffnenZeposia · 4.8 · Hypertension was reported as an adverse reaction in 1.2% of patients treated with ozanimod 0.92 mg and none in
Eintrag öffnenZeposia · 4.8 · In MS clinical studies, bradycardia was reported in 0.5% of patients treated with ozanimod versus 0% of patien
Eintrag öffnenZeposia · 4.8 · In MS clinical studies, first-degree atrioventricular block was reported in 0.6% (5/882) of patients treated w
Eintrag öffnenZeposia · 4.8 · In UC clinical studies, during the induction period, bradycardia was reported on the day of treatment initiati
Eintrag öffnenZeposia · 4.8 · In UC clinical studies, during the induction period, elevations of ALT to 5-fold the ULN or greater occurred i
Eintrag öffnenZeposia · 4.8 · In UC clinical studies, during the induction period, patients treated with ozanimod had an average increase of
Eintrag öffnenZeposia · 4.8 · In UC clinical studies, during the induction period, the overall rate of infections and rate of serious infect
Eintrag öffnenZeposia · 4.8 · In UC clinical studies, herpes zoster was reported in 0.4% of patients who received ozanimod 0.92 mg and none
Eintrag öffnenZeposia · 4.8 · Increased blood pressure In MS clinical studies, patients treated with ozanimod had an average increase of app
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