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Bortezomib Accord · 4.5 · A drug-drug interaction study assessing the effect of rifampicin, a potent CYP3A4 inducer, on the pharmacokine
Eintrag öffnenBortezomib Accord · 4.5 · A drug-drug interaction study assessing the effect of rifampicin, a potent CYP3A4 inducer, on the pharmacokine
Eintrag öffnenBortezomib Accord · 4.5 · During clinical studies, hypoglycaemia and hyperglycaemia were uncommonly and commonly reported in diabetic pa
Eintrag öffnenBortezomib Accord · 4.5 · During clinical studies, hypoglycaemia and hyperglycaemia were uncommonly and commonly reported in diabetic pa
Eintrag öffnenBortezomib Accord · 4.5 · In the same drug-drug interaction study assessing the effect of dexamethasone, a weaker CYP3A4 inducer, on the
Eintrag öffnenBortezomib Accord · 4.5 · In the same drug-drug interaction study assessing the effect of dexamethasone, a weaker CYP3A4 inducer, on the
Eintrag öffnenBortezomib Accord · 4.5 · In vitro studies indicate that bortezomib is a weak inhibitor of the cytochrome P450 (CYP) isozymes 1A2, 2C9,
Eintrag öffnenBortezomib Accord · 4.5 · In vitro studies indicate that bortezomib is a weak inhibitor of the cytochrome P450 (CYP) isozymes 1A2, 2C9,
Eintrag öffnenBortezomib Accord · 4.6 Fertility, pregnancy and lactation · 1
Eintrag öffnenBortezomib Accord · 4.6 Fertility, pregnancy and lactation · 2
Eintrag öffnenBortezomib Accord · 4.8 Undesirable effects · 1
Eintrag öffnenBortezomib Accord · 4.8 Undesirable effects · 2
Eintrag öffnenBortezomib Accord · 4.8 · 14 System Organ Class Incidence Adverse reaction Neoplasms Rare Neoplasm malignant, Leukaemia plasmacytic, Ren
Eintrag öffnenBortezomib Accord · 4.8 · 15 System Organ Class Incidence Adverse reaction Rare Cerebral haemorrhage*, Haemorrhage intracranial (inc sub
Eintrag öffnenBortezomib Accord · 4.8 · 16 System Organ Class Incidence Adverse reaction Gastrointestinal Very Common Nausea and vomiting symptoms*, D
Eintrag öffnenBortezomib Accord · 4.8 · 17 System Organ Class Incidence Adverse reaction Reproductive Uncommon Vaginal haemorrhage, Genital pain*, Ere
Eintrag öffnenBortezomib Accord · 4.8 · 18 BzR-CAP arm that were considered by investigators to have at least a possible or probable causal relationsh
Eintrag öffnenBortezomib Accord · 4.8 · 19 System Organ Class Incidence Adverse reaction Hepatobiliary Common Hepatotoxicity (inc liver disorder) diso
Eintrag öffnenBortezomib Accord · 4.8 · 20 Table 9: Incidence of peripheral neuropathy during induction treatment by toxicity and treatment discontinu
Eintrag öffnenBortezomib Accord · 4.8 · 21 Retreatment of patients with relapsed multiple myeloma In a study in which bortezomib retreatment was admin
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