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20 angezeigte Treffer · Seite 2, keine Gesamtzahl für „ceritinib“
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Begriffe & Kennungen
Zykadia · 4.5 · Ceritinib has been classified in vivo as a strong CYP3A4 inhibitor and has the potential to interact with medi
Eintrag öffnenZykadia · 4.5 · Ceritinib has been classified in vivo as a strong CYP3A4 inhibitor and has the potential to interact with medi
Eintrag öffnenZykadia · 4.5 · Ceritinib should be taken with food. The bioavailability of ceritinib is increased in the presence of food.
Eintrag öffnenZykadia · 4.5 · Ceritinib should be taken with food. The bioavailability of ceritinib is increased in the presence of food.
Eintrag öffnenZykadia · 4.5 · For patients who develop a concurrent medical condition and are unable to take ceritinib with food, ceritinib
Eintrag öffnenZykadia · 4.5 · For patients who develop a concurrent medical condition and are unable to take ceritinib with food, ceritinib
Eintrag öffnenZykadia · 4.5 · In clinical studies, QT prolongation was observed with ceritinib. Therefore, ceritinib should be used with cau
Eintrag öffnenZykadia · 4.5 · In clinical studies, QT prolongation was observed with ceritinib. Therefore, ceritinib should be used with cau
Eintrag öffnenZykadia · 4.5 · P-gp inhibitors Based on in vitro data, ceritinib is a substrate of the efflux transporter P-glycoprotein (P-g
Eintrag öffnenZykadia · 4.5 · P-gp inhibitors Based on in vitro data, ceritinib is a substrate of the efflux transporter P-glycoprotein (P-g
Eintrag öffnenZykadia · 4.5 · Strong CYP3A and P-gp inducers In healthy subjects, co-administration of a single 750 mg fasted ceritinib dose
Eintrag öffnenZykadia · 4.5 · Strong CYP3A and P-gp inducers In healthy subjects, co-administration of a single 750 mg fasted ceritinib dose
Eintrag öffnenZykadia · 4.5 · Strong CYP3A inhibitors In healthy subjects, co-administration of a single 450 mg fasted ceritinib dose with k
Eintrag öffnenZykadia · 4.5 · Strong CYP3A inhibitors In healthy subjects, co-administration of a single 450 mg fasted ceritinib dose with k
Eintrag öffnenZykadia · 4.8 · ADRs with an incidence of ≥10% in patients treated with ceritinib 750 mg fasted were diarrhoea, nausea, vomiti
Eintrag öffnenZykadia · 4.8 · ADRs with an incidence of ≥10% in patients treated with ceritinib 750 mg fasted were diarrhoea, nausea, vomiti
Eintrag öffnenZykadia · 4.8 · Across seven clinical studies, 168 out of 925 patients (18.2%) treated with ceritinib were aged 65 years or ol
Eintrag öffnenZykadia · 4.8 · Across seven clinical studies, 168 out of 925 patients (18.2%) treated with ceritinib were aged 65 years or ol
Eintrag öffnenZykadia · 4.8 · Adverse drug reactions (ADRs) described below reflect exposure to ceritinib 750 mg once daily fasted in 925 pa
Eintrag öffnenZykadia · 4.8 · Adverse drug reactions (ADRs) described below reflect exposure to ceritinib 750 mg once daily fasted in 925 pa
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