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Kisplyx · 4.8 · In CLEAR (see section 5.1), hypothyroidism occurred in 47.2% of patients in the lenvatinib plus pembrolizumab-
Eintrag öffnenKisplyx · 4.8 · In CLEAR (see section 5.1), the most commonly reported liver-related adverse reactions in the lenvatinib plus
Eintrag öffnenKisplyx · 4.8 · In RCC patients treated with lenvatinib and everolimus, patients with baseline renal impairment had higher inc
Eintrag öffnenKisplyx · 4.8 · In RCC patients treated with lenvatinib and everolimus, those with low body weight (<60 kg) had a higher incid
Eintrag öffnenKisplyx · 4.8 · In the paediatric Studies 216 and 231 (see section 5.1), the overall safety profile of lenvatinib as a single
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, 1.3% of patients developed renal failure
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, GI perforation events were reported in 3.
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, QTcF interval increases greater than 60 m
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, arterial thromboembolic events were repor
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, cardiac dysfunction events were reported
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, diarrhoea was reported in 69.0% of patien
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, elderly patients (≥75 years) had a higher
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, females had a higher (≥10% difference) in
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, fistula formation events were reported in
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, haemorrhage events were reported in 28.6%
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, hypertension was reported in 42.5% of pat
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, hypocalcaemia was reported in 4.8% of pat
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, hypothyroidism occurred in 24.1% of patie
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, patients with baseline diabetes had a hig
Eintrag öffnenKisplyx · 4.8 · In the pooled RCC population treated with lenvatinib and everolimus, proteinuria was reported in 34.8% of pati
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